Arrowhead Research Corp. ARWR shares dipped 24.86% to $6.81 after the company announced the FDA clinical hold on its Hepatitis B study.

 SanDisk Corp. SNDK shares dropped 11.81% to $85.58 after the company lowered its Q4 sales outlook.

 Sarepta Therapeutics, Inc.SRPT shares declined 11.47% to $12.35 after releasing results of its Phase IIb open-label extension study of eteplirsen in patients with Duchenne muscular dystrophy (DMD).

 Tiffany & Co. TIF shares tumbled 10.98% to $92.09 after the company reported holiday-period sales results and lowered its FY outlook. In the Americas, Tiffany's total sales on a constant-exchange-rate basis were equal to the earlier year.

 Sanchez Energy Corporation SN slipped 10.70% to $7.93. Crude oil futures fell 3.97% to trade at $46.44 a barrel.

 Tenet Healthcare Corp. THC shares fell 5.15% to $48.99. Tenet Healthcare expected FY2015 earnings of $1.32 to $2.40 per share on sales of $17.40 billion to $17.70 billion.

 Canadian Natural Resources Limited CNQ dropped 4.40% to $26.71 after the company lowered its capital spending plans and production outlook for the full year.

 Shire plc SHPG shares dipped 1.22% to $214.83 after the company agreed to buy NPS Pharmaceuticals Inc NPSP for $5.2 billion, or $46 per share.

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