Today's Morning Top Gainers (DEPO,AVII,BRCD,CRXX,UCTT)

DepoMed, Inc. (NASDAQ: DEPO) is the top percentage gainers in morning trade and surged 26.30% today to $5.57 on huge volume of 3.40 million shares after it today announced top-line results from a Phase 3 clinical trial demonstrating DM-1796 (also referred to as gabapentin ER) achieved a statistically significant reduction in pain associated with postherpetic neuralgia (PHN) versus placebo using the baseline observation carried forward (BOCF) method required by FDA. The primary endpoint measured pain scores from baseline to the end of a ten-week treatment period using the numerical Likert pain scale.

AVI BioPharma, Inc. (NASDAQ: AVII) rallied 25% on 16.75 million shares and now trades at $1.95 after it received expanded contract funding of about $11.5 million from the U.S. Department of Defense to develop its drug candidate for the treatment of Junin virus infection.

Brocade Communications Systems, Inc. (NASDAQ: BRCD) is also moving higher by 17% to $8.94 on 55 million shares after a report the network gear and data storage company is up for sale.

CombinatoRx, Incorporated (NASDAQ: CRXX) soared 21% now trades at $1.55 on an unusual volume of 1.72 million shares after today it announced that its ophthalmic collaborator, Fovea Pharmaceuticals SA, has entered into a proposed acquisition with Sanofi-Aventis. A CombinatoRx-derived combination drug candidate, Prednisporin, (FOV1101), which is a fixed dose combination of prednisolone and cyclosporine, is the most advanced product asset in the Fovea pipeline, with Phase 2b clinical studies planned for the treatment of persistent allergic conjunctivitis.

Ultra Clean Holdings, Inc. (NASDAQ: UCTT) jumped up 14.34% to $5.66 on 182K shares after Needham & Co upgrades the stock to Buy from Hold. Price target $8.. In the morning trade the stock made a new 52-week high at $5.94.