Top Losers

  Intra-Cellular Therapies Inc (NASDAQ: ITCI) shares tumbled 63.2 percent to $15.60 after its lead product candidate, ITI-007, failed a late-stage study in schizophrenia. Apparently, the drug couldn't beat the placebo, nor could it equal the performance of the active control...

  Caesars Entertainment Corp (NASDAQ: CZR) shares declined 14.9 percent to $8.05. Caesars Entertainment and Caesars Entertainment Operating Co. announced key economic terms of proposed consensual restructuring plan for CEOC. Alliance One International, Inc. (NYSE: AOI) shares fell 14...

  Pain Therapeutics, Inc. (NASDAQ: PTIE) shares dipped 53.6 percent to $1.27 after the company reported that it has received a complete response letter from the FDA. The FDA determined that REMOXY cannot be approved. DURECT Corporation (NASDAQ: DRRX) shares dropped 32.7 percent to $1....

  Enphase Energy Inc (NASDAQ: ENPH) shares dropped 26.1 percent to $1.24 after disclosing restructuring and cost reduction initiatives, which are expected to result in annualized savings of approximately $20 million. The plan includes an 11 percent reduction of the company’s global...

  OMNOVA Solutions Inc. (NYSE: OMN) dropped 13.4 percent to $8.70 after the company reported weaker-than-expected Q3 earnings. Great Basin Scientific Inc (NASDAQ: GBSN) shares fell 13.3 percent to $2.96. Great Basin Scientific shares have tumbled 99.98 percent over the past 52 weeks...

  Mast Therapeutics Inc (NYSE: MSTX) shares tumbled 80.3 percent to $0.116 after the company announced its phase-3 EPIC trial of vepoloxamer for the treatment of sickle cell disease patients experiencing vaso-occlusive crisis failed to meet its primary efficacy endpoint. Mirna...

  MGT Capital Investments Inc. (NYSE: MGT) shares dipped 29.4 percent to $1.78 after the company issued an update on status of D-Vassive acquisition. The company has been told that it cannot list 43.8 million shares on the NYSE to close D-Vassive merger. MGT Capital still remains...

  Vical Incorporated (NASDAQ: VICL) shares tumbled 24.3 percent to $2.92 after the company disclosed that its Phase 2 trial did not meet primary endpoint. MGT Capital Investments Inc. (NYSE: MGT) dropped 15.8 percent to $2.74 as the company reported that it has received a subpoena...

  Novavax, Inc. (NASDAQ: NVAX) shares tumbled 82.9 percent to $1.43 after reporting disappointing results from two Phase 3 vaccine trials that had previously done well in the Phase 2 trial. According to the company, data from the Resolve Phase 3 trial for its vaccine for a potentially...

  Energy Fuels Inc Ordinary Shares (Canada) (NYSE: UUUU) shares declined 22.9 percent to $1.75 after announcing a $10 million bought-deal offering of units. Misonix, Inc. (NASDAQ: MSON) shares tumbled 17.1 percent to $5.08 as the company filed for extension of time for its Annual...

  RF Industries, Ltd. (NASDAQ: RFIL) shares fell 17.6 percent to $1.80. RF Industries reported a Q3 loss of $0.07 per share, versus year-ago earnings of $0.02 per share. LifeVantage Corp (NASDAQ: LFVN) shares dropped 17.2 percent to $8.61 after announcing a delay in the release of...

  Applied Genetic Technologies Corp (NASDAQ: AGTC) shares tumbled 32.8 percent to $8.86. Applied Genetic Technologies reported Q4 earnings of $0.15 per share on revenue of $12.1 million. Janney Capital downgraded Applied Genetic Tech from Buy to Sell, while Wells Fargo downgraded the...

  Geron Corporation (NASDAQ: GERN) shares declined 17.1 percent to $2.37 after the company issued an update on imetelstat trials being conducted by Janssen Research & Development, LLC. SigmaTron International (NASDAQ: SGMA) dropped 10.8 percent to $5.81 following Q1 results....

  Gevo, Inc. (NASDAQ: GEVO) shares tumbled 28.6 percent to $0.500. Gevo priced $15.6 million offering of common stock and warrants. Tractor Supply Company (NASDAQ: TSCO) declined 15.7 percent to $70.38 as the company lowered its full-year forecast. Several analysts downgraded the...

  Shiloh Industries, Inc. (NASDAQ: SHLO) shares dropped 20.6 percent to $6.98. Shiloh Industries reported Q3 earnings of $0.02 per share on sales of $248.8 million. HD Supply Holdings Inc (NASDAQ: HDS) shares dipped 14.2 percent to $31.11 as the company reported below than expected...