Aeterna Zentaris (NASDAQ:

) shares dipped 48.06% to $0.67 after the company announced that it has received a complete response letter from the FDA for Macrilen. Solazyme (NASDAQ:

) shares dropped 48.01% to $3.89 after the company reported a Q3 loss of $0.45 per share on revenue of $17.60 million and launched a partnership with Versalis to commercialize Encapso. Cowen & Company downgraded Solazyme from Outperform to Market Perform.. Genworth Financial (NYSE:

) slipped 35.61% to $9.06 following Wednesday's earnings miss. Senomyx (NASDAQ:

) shares dropped 31.74% to $4.86 after the company reported downbeat quarterly results and issued a weak revenue forecast. Web.com Group (NASDAQ:

) shares fell 24.35% to $15.32 after the company reported Q3 earnings of $0.63 per share on revenue of $143.80 million and announced a $100 million stock repurchase authorization. JP Morgan downgraded Web.com Group from Overweight to Neutral and lowered the price target from $35.00 to $20.00. Epizyme (NASDAQ:

) dropped 21.47% to $20.89 after the company reported the publication of preliminary findings from Phase 1 study of DOT1L Inhibitor EPZ-5676 in ASH Annual Meeting Abstract. Tangoe (NASDAQ:

) dipped 19.95% to $11.72 after the company reported weaker-than-expected quarterly results and issues a downbeat outlook. Analysts at Raymond James downgraded Tangoe from Strong Buy to Market Perform and removed the price target of $19. Textura (NYSE:

) slipped 17.46% to $21.89 after the company reported Q3 results and issued a weak guidance. Cornerstone OnDemand (NASDAQ:

) shares declined 17.16% to $27.13 after the company reported a Q3 loss of $0.27 per share on revenue of $68.30 million and issued a weak sales forecast. Barclays lowered the price target on Cornerstone OnDemand from $52.00 to $40.00 Zillow (NASDAQ:

) shares tumbled 4.14% to $99.47 after the company reported Q3 results. JMP Securities lowered the price target on Zillow from $155.00 to $140.00.