Daré Bioscience Shares Move Higher Intravaginal Ring Shows Promise In Menopause Symptoms

Daré Bioscience Inc DARE announced topline PK results from its Phase 1 / 2 trial of DARE-HRT1, an investigational intravaginal ring (IVR) designed to deliver bio-identical 17β-estradiol and bio-identical progesterone continuously over a 28-day period as part of an HT regimen.
HT treats vasomotor symptoms (VMS) and genitourinary syndrome associated with menopause.
The levels of estradiol released from the lower and higher dose formulation of DARE-HRT1 evaluated in the study achieved or exceeded the levels targeted for hormone therapy.
Related: Daré Bioscience's Intravaginal Ring Improves Vasomotor, Vaginal Symptoms Of Menopause.
The levels of progesterone released from both versions of DARE-HRT1 evaluated in the study met the objectives of releasing progesterone.
Estradiol levels released from the lower and higher dose formulation of DARE-HRT1 evaluated in the study achieved statistically significant improvement in VMS and the genitourinary symptoms of menopause and vaginal pH and maturation index.
Menopausal symptoms, including hot flashes and night sweats, were reduced compared with baseline in both DARE-HRT1 dose groups.
Participants also showed significant improvement from baseline in all measures surveyed on The Menopausal Quality of Life Survey.
The study treatment was well tolerated.
Daré intends to seek FDA approval of DARE-HRT1 for moderate to severe VMS due to menopause in women with intact uteri.
Price Action: DARE shares are up 3.20% at $1.01 on the last check Monday.

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