U.S. stocks were mixed, with the Dow Jones index falling more than 50 points on Thursday.

Shares of Taysha Gene Therapies Inc (NASDAQ:TSHA) rose sharply during Thursday's session after the FDA granted the company Breakthrough Therapy designation to TSHA-102 for the treatment of Rett syndrome.

Needham analyst Gil Blum maintained Taysha Gene Therapies with a Buy and raised the price target from $8 to $10.

Taysha Gene Therapies shares jumped 50.4% to $4.78 on Thursday.

Here are some other big stocks recording gains in today’s session.

  • Bakkt Holdings Inc (NYSE:BKKT) gained 37.2% to $46.81. Bakkt completed the sale of Loyalty Business.
  • Canaan Inc – ADR (NASDAQ:CAN) shares surged 29.8% to $1.35 after the Bitcoin (CRYPTO: BTC) mining machine manufacturer announced a landmark sales order.
  • Ondas Holdings Inc (NYSE:ONDS) gained 25.5% to $9.18 after the company announced an initial order of 500 Wasp drones from Rift Dynamics to launch US defense market distribution through its American Robotics unit.
  • Angel Studios Inc (NYSE:ANGX) gained 20.6% to $9.42.
  • Fair Isaac Corp (NYSE:FICO) surged 19.6% to $1,811.61 after the company launched its FICO Mortgage Direct License Program. Under the program tri-merge resellers are able to calculate and distribute FICO Scores directly to customers.
  • Kodiak AI Inc (NASDAQ:KDK) surged 16.8% to $6.96.
  • Sarepta Therapeutics Inc (NASDAQ:SRPT) gained 16.1% to $22.43.
  • USA Rare Earth Inc (NASDAQ:USAR) rose 15.7% to $21.31.
  • Rigetti Computing Inc (NASDAQ:RGTI) gained 14.6% to $34.22.
  • Cipher Mining Inc (NASDAQ:CIFR) surged 12.8% to $14.22.
  • AST SpaceMobile Inc (NASDAQ:ASTS) jumped 12.3% to $63.98 after the company announced that it completed final assembly and testing of its BlueBird 6 satellite.
  • Diginex Ltd (NASDAQ:DGNX) gained 11.7% to $16.26.
  • D-Wave Quantum Inc (NYSE:QBTS) surged 10.5% to $28.33.
  • SoundHound AI Inc (NASDAQ:SOUN) gained 10.6% to $17.87.
  • Joby Aviation Inc (NYSE:JOBY) rose 9.3% to $17.72.
  • Oklo Inc (NYSE:OKLO) gained 8.1% to $125.36.
  • Applied Digital Corp (NASDAQ:APLD) shares jumped 7.7% to $26.93. Shares of crypto-linked stocks traded higher amid a rise in Bitcoin. The digital token may be seeing strength due to the ongoing government shutdown.

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