Mirati Therapeutics, Inc. (NASDAQ: MRTX) shares touched a new 52-week low of $6.54. Mirati Therapeutics shares have dropped 78.59 percent over the past 52 weeks, while the S&P 500 index has declined 1.84 percent in the same period.

Adamis Pharmaceuticals Corp (NASDAQ: ADMP) shares touched a new 52-week low of $2.96. Adamis Pharmaceuticals shares have tumbled 27.86 percent over the past 52 weeks, while the S&P 500 index has dropped 1.84 percent in the same period.

CVR Refining LP (NYSE: CVRR) shares reached a new 52-week low of $8.16. CVR Refining shares have dipped 54.56 percent over the past 52 weeks, while the S&P 500 index has slipped 1.84 percent in the same period.

Lipocine Inc (NASDAQ: LPCN) shares touched a new 52-week low of $6.55. Lipocine shares have dropped 12.78 percent over the past 52 weeks, while the S&P 500 index has declined 1.84 percent in the same period.