New information regarding RhuDex(TM)

LUND, SWEDEN--(Marketwire - August 7, 2009) - Active Biotech AB's (NASDAQ OMX Nordic: ACTI) collaboration partner MediGene AG (Frankfurt: MDG, Prime Standard, TecDAX) today announce information regarding the candidate drug RhuDexT for the treatment of rheumatoid arthritis.

In cooperation with the British drug regulatory authority MHRA (Medicines and Healthcare Products Regulatory Agency), MediGene has conducted a series of in-vitro studies to rule out any potential detrimental interaction between RhuDexT and arteriosclerotic blood vessels.

The results are now submitted to the regulatory authority for appraisal. Upon approval of the authorities, clinical development of the drug candidate may be resumed before the end of this year.

To read the complete press release, please see www.medigene.com.

Lund, August 7, 2009 Active Biotech AB (publ) Tomas Leanderson President and CEO

Notes to editors

About RhuDexT

RhuDex is a novel, orally available compound for the treatment of rheumatoid arthritis, originating from Active Biotech's patented CD80 antagonists, out-licensed to MediGene AG. RhuDex is being developed as a disease-modifying drug for the treatment of rheumatic diseases.

About Active Biotech

Active Biotech AB (NASDAQ OMX NORDIC: ACTI) is a biotechnology company with focus on autoimmune/inflammatory diseases and cancer. Projects in pivotal phase are laquinimod, an orally administered small molecule with unique immunomodulatory properties for the treatment of multiple sclerosis, as well as ANYARA for use in cancer targeted therapy, primarily of renal cancer. Further key projects in clinical development comprise the three orally administered compounds TASQ for prostate cancer, 57-57 for SLE and RhuDexT for RA. Please visit www.activebiotech.com for more information.

Active Biotech AB PO Box 724, SE-220 07 Lund Sweden Tel: +46 (0)46-19 20 00 Fax: +46 (0)46-19 11 00

Active Biotech is required under the Securities Markets Act to make the information in this press release public. The information was submitted for publication at 08:30 a.m. CET on August 7, 2009.

This announcement was originally distributed by Hugin. The issuer is solely responsible for the content of this announcement.

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