15 Biggest Mid-Day Losers For Tuesday

Proteon Therapeutics Inc PRTO tumbled 74.3 percent to $2.55 after the company disclosed that it did not meet primary endpoint in PATENCY-1 trial.
Inovalon Holdings Inc INOV dropped 35.6 percent to $9.60 as the company cut its earnings and revenue guidance for full year 2016.
Apricus Biosciences Inc APRI shares fell 23.5 percent to $1.37. Apricus Biosciences shares have jumped 110.59 percent over the past 52 weeks, while the S&P 500 index has gained 11.62 percent in the same period.
aTyr Pharma Inc LIFE shares dipped 20.6 percent to $2.90 after the company disclosed clinical results from exploratory trials with Resolaris.
LifeVantage Corp LFVN shares fell 15.5 percent to $8.19. LifeVantage reported Q1 earnings of $0.13 per share on revenue of $54.9 million.
Anavex Life Sciences Corp. AVXL shares dropped 13.2 percent to $4.23. Anavex Life Sciences shares have dropped 35.87 percent over the past 52 weeks, while the S&P 500 index has gained 11.62 percent in the same period.
Endologix, Inc. ELGX shares declined 9.4 percent to $6.24 as the company disclosed that it has received suspension of CE Mark for AFX System.
Globus Maritime Ltd GLBS shares fell 7.4 percent to $5.81 after climbing 5.03 percent on Monday.
National Storage Affiliates Trust NSA fell 6.6 percent to $20.80. National Storage Affiliates Trust prices its public offering of 4.5 million common shares for gross proceeds of around $94.5 million.
BioDelivery Sciences International, Inc. BDSI dropped 6.3 percent to $1.88 after the company disclosed that its Clonidine Topical Gel Phase 2b trial missed the primary endpoint.
Arbutus Biopharma Corp ABUS slipped 5.1 percent to $ 2.80 after the company issued additional data from its ARB-1467 Phase II trial in HBV patients. Chardan Capital downgraded Arbutus Biopharma from Buy to Neutral and lowered the price target from $4.00 to $3.00.
Alexion Pharmaceuticals, Inc. ALXN fell 3.5 percent to $111.09. Morgan Stanley downgraded Alexion Pharmaceuticals from Overweight to Equal-Weight.
Hancock Holding Company HBHC shares declined 3 percent to $42.70. Hancock Holding disclosed a 5 million share common stock offering.
Buffalo Wild Wings BWLD slipped 2.5 percent to $170.02. BMO Capital downgraded Buffalo Wild Wings from Outperform to Market Perform.
Littelfuse, Inc. LFUS dropped 2.2 percent to $152.08. Longbow Research downgraded Littelfuse from Buy to Neutral.