15 Biggest Mid-Day Losers For Thursday

Pacific Biosciences of California PACB shares tumbled 40.4 percent to $4.11 after the company reported the termination of agreement with Roche Diagnostics around the company company's Single Molecule, Real-Time technology.
Ocean Rig UDW Inc. ORIG shares dipped 21.2 percent to $1.78 as the company reported weaker-than-expected earnings for its third quarter on Wednesday.
Amicus Therapeutics, Inc. FOLD declined 12.7 percent to $5.11 after the company reported a proposed offering of convertible senior notes due 2023.
Merus Labs International Inc (USA) MSLI shares declined 11.9 percent to $0.740. On Wednesday, Merus Labs posted Q4 adjusted EBITDA of $11.6 million and gross basis revenue of $34.3 million. CIBC downgraded Merus Labs from Outperform to Neutral.
First Majestic Silver Corp AG shares fell 10.9 percent to $7.30. Silver futures dropped 6.7 percent to trade at $16.08 an ounce.
Gulfport Energy Corporation GPOR dropped 10.8 percent to $23.97. Gulfport launched a 29 million offering of common stock.
Avino Silver and Gold Mines Ltd ASM shares slipped 10.4 percent to $1.21.
Yamana Gold Inc. (USA) AUY shares declined 10.3 percent to $2.52. Gold futures slipped 3 percent to trade at $1,128.80 an ounce.
IAMGOLD Corp (USA) IAG shares fell 9.3 percent to $3.23 after declining 9.64 percent on Wednesday. Gold futures slipped 3 percent to trade at $1,128.80 an ounce.
MAG Silver Corp (USA) MAG shares declined 9.3 percent to $10.31.
Coeur Mining Inc CDE shares fell 8 percent to $9.06 after dropping 4.65 percent on Wednesday.
Valeant Pharmaceuticals Intl Inc VRX shares fell 7 percent to $13.13. Morgan Stanley downgraded Valeant from Overweight to Equal-Weight and lowered the price target from $25.00 to $17.00.
AngloGold Ashanti Limited (ADR) AU shares declined 6.7 percent to $9.41 after dropping 6.75 percent on Wednesday.
Simmons First National Corporation SFNC dropped 6 percent to $60.90shares gained 18.7 percent to $28.25. Simmons First National announced plans to acquire Southwest Bancorp, Inc. OKSB in a deal valued at around $564.4 million.
Stone Energy Corporation SGY shares fell 3.3 percent to $5.94 after the company disclosed that it has files for court approval of restructuring plan. The company has filed for Chapter 11 Bankruptcy.