- EnteroMedics Inc ETRM shares fell 34.8 percent to $5.80. EnteroMedics reported the pricing of $16.5 million underwritten public offering at $5.31 per unit.
- Pulmatrix Inc PULM shares tumbled 31 percent to $1.07. Pulmatrix shares jumped Tuesday after the company disclosed that its drug candidate, PUR1900, has received "Qualified Infectious Disease Product" designation from the FDA.
- Gigamon Inc GIMO shares declined 29.6 percent to $31.00 after the company lowered its Q4 earnings guidance.
- Pearson PLC (ADR) PSO shares dropped 29 percent to $7.09 after the company lowered its profit forecast for the year and cut its dividend.
- Benitec Biopharma Ltd (ADR) BNTC shares declined 21.3 percent to $2.36. Benitec Biopharma shares climbed Tuesday after the company disclosed that it has received Orphan Drug Designation in the European Union for BB-301 for the treatment of oculopharyngeal muscular dystrophy.
- Iradimed Corp IRMD fell 19.4 percent to $9.79 after the company issued a weak forecast for the first quarter.
- Biocept Inc BIOC declined 14 percent to $1.57. Biocept shares have dropped 56.43 percent over the past 52 weeks, while the S&P 500 index has gained 20.55 percent in the same period.
- Cameco Corp (USA) CCJ dropped 13.5 percent to $11.48. Cameco projects to post loss for 2016 and announced plans to cut 10 percent of its workforce.
- Bonanza Creek Energy Inc BCEI shares slipped 12.7 percent to $2.62. Bonanza Creek Energy reported that it received an unsolicited inquiry from Bill Barrett Corporation.
- MYOS RENS Technology Inc MYOS dropped 9.1 percent to $3.49. MYOS RENS Technology shares have surged 138.07 percent over the past 52 weeks, while the S&P 500 index has gained 20.55 percent in the same period.
- Mercantile Bank Corp. MBWM declined 7.3 percent to $32.89. Raymond James downgraded Mercantile Bank from Outperform to Market Perform.
- Target Corporation TGT fell 5 percent to $67.42 after the company lowered its sales and profit guidance for fourth quarter. The company’s same-store sales dropped 1.3 percent in the November to December holiday period.
- Goldman Sachs BDC Inc GSBD dropped 3 percent to $23.17. Wells Fargo downgraded Goldman Sachs BDC from Outperform to Market Perform.
- CSX Corporation CSX shares fell 2.7 percent to $37.06. CSX reported Q4 earnings of $0.49 per share on revenue of $3.037 billion.
- Kohl's Corporation KSS slipped 2.7 percent to $40.25. Credit Suisse downgraded Kohl's from Neutral to Underperform.
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