10 Biggest Mid-Day Losers For Wednesday

Aldeyra Therapeutics Inc ALDX shares dropped 12.3 percent to $4.47 after the company disclosed that its Phase 2b trial did not meet primary endpoint.
Hawaiian Holdings, Inc. HA shares tumbled 10.5 percent to $48.90. Stifel Nicolaus downgraded Hawaiian from Hold to Sell and lowered the price target from $60.00 to $40.00.
Liberty Tax Inc TAX shares declined 10.4 percent to $11.60 after the company reported weak Q4 earnings.
Synchronoss Technologies, Inc. SNCR shares dipped 9.1 percent to $11.03.
Whiting Petroleum Corp WLL shares declined 8.8 percent to $6.15 after gaining 9.61 percent on Tuesday.
Teekay Offshore Partners L.P. TOO shares dropped 8.2 percent to $2.35.
Horizon Bancorp HBNC shares declined 5.7 percent to $25.93. Horizon Bancorp announced plans to merge with WOLVERINE BANCORP, INC. WBKC.
Epizyme Inc EPZM shares fell 5 percent to $10.60 after the company reported interim data from Phase 2 trial for tazemetostat in relapsed or refractory follicular lymphoma and DLBCL patients.
Five Below Inc FIVE tumbled 4.2 percent to $48.85. KeyBanc downgraded Five Below from Overweight to Sector Weight.
Anadarko Petroleum Corporation APC shares dropped 3.8 percent to $47.35. Barclays downgraded Anadarko Petroleum from Equal-Weight to Underweight.