Opinion: Compounded semaglutide is an ill-defined public health crisis

I first met Jane (not her real name, of course) on a Friday afternoon in our clinic. She was referred for further evaluation of her chest pain, which, in the context of her family history of early-onset heart attacks and her morbid obesity, understandably concerned her primary care doctor.

In the exam room, we dissected her symptoms and decided we’d investigate them further with a stress test. We also discussed her weight. It was clear from our conversation that Jane was motivated. For months, she had closely watched what she ate. She took walks during her lunch break in an office park and regularly went to the gym. She tried stress relaxation techniques like meditation. She made sure that she got enough sleep.

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