Lexaria Bioscience Corp LEXX has announced that its tolerability and pharmacokinetic study VIRAL-A20-3 has been completed with positive results.
- The study demonstrated that DehydraTECH enabled colchicine, one of the products tested by Lexaria with known SARS-CoV-2 antiviral properties, benefited from its proprietary formulation and processing, resulting in increased delivery.
- Colchicine is occasionally recommended and used to treat emergent pericarditis in children when cardiac inflammation develops following administration of mRNA COVID-19 vaccines.
- It has shown potent effects in mitigating the cytokine storm associated with COVID-19.
- Study VIRAL-A20-3 was performed using 20 rats dosed via oral gavage using either DehydraTECH or control colchicine formulations.
- The study evaluated peak concentration and total drug delivery into the rodent bloodstream.
- Colchicine achieved 31.9 ng/mL of peak concentration, compared to 16.7 ng/mL in the control group.
- Total drug delivery for colchicine reached 104.4 ng/mL versus 38.97 ng/mL for the control arm.
- Price Action: LEXX shares are up 50.50% at $9.92 during the premarket session on the last check Wednesday.
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