Preclinical Data Of Brain Tumor Candidate Fails To Lift Lantern Pharma Stock

  • Lantern Pharma Inc LTRN announced preclinical data of its drug candidate LP-184, showing its potential to inhibit tumor growth and improve survival in animals models of glioblastoma (GBM).
  • LP-184 treatment induced tumor regression evidenced by greater than 106% tumor growth inhibition in two subcutaneous xenograft models of GBM (U87 and M1123). 
  • LP-184 also prolonged survival in mice bearing an intracranially implanted tumor model of GBM (U87) compared with those that did not receive any drug substance. 
  • Intravenous administration of LP-184 over two cycles reduced subcutaneous xenograft tumor volume in mice by greater than 85% within the treatment group. 
  • Lantern expects to further refine the dosing regimen and cycle in the next phase of work, hoping that additional improvements in survival can be translated into human clinical trials.
  • LTRN stock has lost 21.70% in the last month.
  • Price Action: LTRN shares are down 5.56% at $11.04 during the market session on the last check Thursday.
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