Exelixis - Takeda's Cabometyx Scores Approval In Japan For Kidney Cancer

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  • Exelixis Inc's EXEL collaborating partner Takeda Pharmaceutical Co Ltd TAK and Ono Pharmaceutical Co Ltd have received approval for Cabometyx (cabozantinib) in Japan.
  • The approval covers Cabometyx combined with Bristol-Myers Squibb Co's BMY Opdivi (nivolumab) for unresectable or metastatic renal cell carcinoma (RCC).
  • The approval is based on the CheckMate 9ER Phase 3 trial. 
  • The Cabometyx combination demonstrated superior overall survival and doubled median progression-free survival and objective response rate versus sunitinib, with a favorable safety profile.
  • Per the terms of Exelixis and Takeda's collaboration and license agreement, Exelixis will receive a milestone payment of $20 million from Takeda. 
  • Related content: Benzinga's Full FDA Calendar.
  • Price Action: TAK stock is down 0.30% at $16.77 during the premarket session on the last check Thursday, and EXEL stock closed 0.11% lower at $18.91 on Wednesday.
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