Prothena Highlinghts New Preclinical Data For Alzheimer's, Parkinson's Vaccine Programs

Prothena Corporation plc PRTA presented new preclinical data from its dual Aβ/tau and tandem C-terminal α-synuclein vaccine programs in Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. 

• The data were presented at the International Conference on Alzheimer's and Parkinson's Diseases (AD/PD 2022).
• The Company plans for an IND for the AD vaccine candidate in 2023.
• Related: Novo Nordisk To Buy Prothena's ATTR Amyloidosis Program For Up To $1.2B.
• The presentation on preclinical data demonstrates Prothena's dual Aβ/tau vaccine for Alzheimer's, generated anti-Aβ and anti-tau antibodies to enable phagocytosis of Aβ and neutralize tau.
• Preclinical data from the tandem C-terminal α-synuclein vaccine for Parkinson's produces robust binding to pathogenic α-synuclein and inhibition of uptake of soluble α-synuclein aggregates into cells.
• Price Action: PRTA shares closed 4.35% higher at $33.33 on Tuesday.