Equillium's Itolizumab Shows Durable Clinical Response In GvHD Patients

Equillium Inc EQ announced two oral presentations on itolizumab at the Annual Meeting of the European Society for Blood and Marrow Transplantation. 

• The presentation includes new findings demonstrating the durability of clinical response out to one year for patients with high-risk acute graft-versus-host disease (aGVHD) treated with itolizumab in the EQUATE study. 
• Data demonstrated that Day 29 complete response (CR) rate was 52% across all dose cohorts, and the overall response rate (ORR) was 64%. 
• Related: Equillium Reveals Early Safety Data For Itolizumab In Lupus Patients.
• The highest Day 29 CR rate of 61% was achieved in subjects treated with itolizumab within 72 hours of starting systemic corticosteroids​. 
• Patients who responded to itolizumab treatment had clinically meaningful reductions in steroid administration with a median decrease in steroid use of 73% by Day 29 and 96% by six months.
• Also Read: Equillium Adds Three Drugs To Its Pipeline Via Bioniz Acquisition.
• Price Action: EQ shares are up 1.52% at $3.34 during the market session on the last check Wednesday.