Immix Biopharma Inc IMMX announced the presentation of updated data from the ongoing Phase 1b/2 NEXICART-1 study of its NXC-201, an autologous, BCMA-targeted chimeric antigen receptor T (CAR-T) cell therapy.
The updated dataset consists of 63 multiple myeloma patients.
95% overall response rate (36 of 38 patients at the therapeutic dose of 800 million CAR+T cells) in relapsed/refractory multiple myeloma who were not exposed to prior BCMA-targeted therapy, producing a median progression-free survival (mPFS) of 12.9 months.
Also Read: Immix Biopharma's Subsidiary Says Investigational CAR T Therapy Shows 100% Response Rate In Amyloidosis.
90% overall response rate (45 of 50 patients at the therapeutic dose of 800 million CAR+T cells) in relapsed/refractory multiple myeloma.
58% complete response rate (29 out of 50 patients at the therapeutic dose of 800 million CAR+T cells)
The overall response rates for each dose level were 50%, 86%, and 90%, respectively.
Favorable NXC-201 safety data support the potential for NXC-201, if ultimately approved, to reduce hospitalization, with an opportunity for use as outpatient CAR-T cell therapy, potentially reducing related hospitalization costs by up to 80%.
Price Action: IMMX shares are up 23.40% at $4.22 on the last check Monday.
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