BriaCell Therapeutics' Cancer Drug Shows Preliminary Survival, Clinical Benefit In Pretreated Patients

Zinger Key Points
  • The disease control rate of 40% was observed in evaluable patients, further indicating clinical benefit.
  • The company is investigating the effects of Bria-IMT regimen in advanced breast cancer with overall survival as its primary endpoint.

BriaCell Therapeutics Corp BCTX reported preliminary survival and clinical benefit data in a new subset of advanced breast cancer patients treated with BriaCell's Bria-IMT regimen: patients that have developed resistance to (and failed to respond to) Antibody-Drug Conjugates (ADCs).

Kaplan-Meier analysis showed median overall survival (OS) that was up to twice that reported in the literature, with some patients recording survival of over a year.

The disease control rate of 40% was observed in evaluable patients, further indicating clinical benefit.

Progression-free survival (PFS) was similar or better than that of the patient's prior therapy in 40% of patients, highlighting the clinical benefit and tolerability of the Bria-IMT regimen.

17 of 23 patients remain alive today, suggesting the efficacy, tolerability, and survival benefit of BriaCell's Bria-IMT regimen. The data will continue to mature as patients remain on the study.

All patients received BriaCell's therapy with no toxicity-related discontinuations.

There were no cases of Interstitial Lung Disease with Bria-IMT – a well-documented serious side effect of ADCs. 

Price Action: BCTX shares are up 4.31% at $4.11 on the last check Wednesday.

Market News and Data brought to you by Benzinga APIs
Comments
Loading...
Posted In: BiotechNewsPenny StocksHealth CareGeneralBriefs
Benzinga simplifies the market for smarter investing

Trade confidently with insights and alerts from analyst ratings, free reports and breaking news that affects the stocks you care about.

Join Now: Free!