Institutional Crypto Adoption 'For Real This Time,' Says Messari

Zinger Key Points
  • The rise of decentralized physical infrastructure networks, Solana’s growth and Ethereum Layer-2 scaling reflect broader market strength.
  • Messari highlights expanding Bitcoin use cases, the intersection of AI and crypto and renewed DeFi and stablecoin innovation.

Institutional adoption of cryptocurrencies is now “for real this time,” according to Messari's 2025 crypto theses report, which highlights the growing presence of traditional finance in digital assets.

What Happened: The report cites approvals of Bitcoin BTC/USD and Ethereum ETH/USD exchange-traded funds (ETFs), increasing involvement from major financial players and the expanding role of tokenized assets as evidence that institutional adoption is firmly underway.

Messari emphasizes that institutional engagement has shifted beyond ETFs, with asset issuance, stablecoin development and broader blockchain applications gaining momentum.

“The institutions are here – this time for real. The approval of the BTC and ETH ETFs has legitimized the asset class and made it more accessible to both retail and institutional allocators,” the report states.

The report also highlights other key developments reshaping the crypto industry, including the rise of decentralized physical infrastructure networks (DePIN), which saw significant growth in sectors like compute, energy and mobility.

The market capitalization of DePIN projects surged by 132% year-over-year, showcasing their role in bridging blockchain infrastructure with real-world applications.

Solana SOL/USD emerged as another standout performer, achieving notable gains in 2024 driven by advancements like the Firedancer upgrade and its dominance in decentralized exchange volumes.

Messari points to Solana's ability to deliver high throughput and lower costs, positioning it as a growing competitor to Ethereum.

Also Read: Bitcoin, Ethereum ETFs See $688M Net Inflows, Analysts Target $124,000

Meanwhile, Ethereum continues to play a central role as Layer-2 scaling solutions gain traction, improving network efficiency and throughput.

The report notes that while Ethereum remains foundational, Layer-2 rollups have outpaced Layer-1 activity, reflecting the platform's evolving role amid market competition.

Messari also explores the expanding Bitcoin ecosystem, where institutional inflows and increasing utility are bolstering Bitcoin’s recognition as a macroeconomic hedge.

The convergence of AI and crypto is another trend identified in the report, with decentralized AI projects like Bittensor TAO/USD driving innovation and enabling new use cases for blockchain technology.

The report further highlights renewed innovation across DeFi, stablecoins,and consumer apps, reflecting broader momentum in the crypto market.

What’s Next: With institutional participation now firmly entrenched and multiple sectors experiencing growth, Messari concludes that the macro environment for crypto adoption has entered a new phase.

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