The SPDR S&P 500 ETF Trust SPY declined by 9.62% in September – its largest decline in 2022. The Fidelity NASDAQ Composite Index ETF ONEQ and the SPDR Dow Jones Industrial Average ETF DIA mimicked this downward trend, showing monthly decreases in September of 10.54% and 8.98%, respectively.
OTC Markets Group Inc.’s OTCM regulated markets experienced a slight increase in total monthly volume, recording $39.5 billion in September compared to $39.3 billion in August.
A Dive Into The OTCQX Best Market’s Most-Active List
The OTCQX Best Market recorded $7.3 billion in trading volume in September, a slight increase over the $6.9 billion traded in August.
Despite Ethereum’s successful completion of the Merge, trading volume in Grayscale Ethereum Trust ETHE waned in September, dropping the security to third on the OTCQX Best Market’s Most Active list. Steadfast performers Roche Holding AG RHHBY and Grayscale Bitcoin Trust GBTC slotted into first and second place, respectively.
Additionally, OTCQX’s top 10 most-active securities experienced a slight reshuffle in September, welcoming previously familiar faces in Danone DANOY and in Deutsche Telekom AG DTEGY and Akzo Nobel N.V. AKZOY. The three newcomers displace BASF SE BASFY, Anglo American PLC NGLOY and Imperial Brands PLC IMBBY in the top 10 most-active securities list.
Other notable movers:
- J Sainsbury PLC JSAIY claimed the 28th spot on the OTCQX’s Most Active list, experiencing a 203% increase in trading volume.
- Koninklijke Ahold Delhaize N.V. ADRNY claimed the 15th spot on the OTCQX’s Most Active list, experiencing a 127% increase in trading volume.
The OTCQB Venture Market Experiences A Reshuffle
The OTCQB Venture Market recorded $642.6 million in trading volume in September, an increase from both July’s $463 million and August’s $601 million trading volume figures.
Like the OTCQX Best Market, the OTCQB Venture Market’s top 10 Most Active list for the month saw new entries. Specifically, Todos Medical Ltd. TOMDF and American Lithium Corp. LIACF made way for Global Tech Industries Group Inc. GTII and Know Labs Inc. KNWN.
Similar to August, the OTCQB Venture Market witnessed a number of novelties in September. In addition to two new companies on the top 10 Most Active List, the constituents of the list experienced a shakeup. Biotechnology company CytoDyn Inc. CYDY, for example, dropped from most traded to seventh-most traded security, while newcomer Global Tech Industries took a giant leap all the way to first place. Lithium miner Lake Resources N.L. LLKKF experienced a similar jump, rising to second place from eighth place last month.
Other notable movers:
- Silver Mountain Resources Inc. AGMRF climbed to 11th place on the Most Active list and recorded an $8.9 million rise in trading volume compared to last month.
- Know Labs Inc. climbed to 10th place on the Most Active list for the OTCQB Venture Market and recorded a $7.7 million rise in trading volume compared to last month.
- BioLargo Inc. BLGO climbed to 23rd place on the Most Active list and recorded a $2.3 million rise in trading volume compared to last month.
The OTCQX And OTCQB Top 10
Below are the top 10 most actively traded securities on the OTCQX Best Market and OTCQB Venture Market in September.
OTCQX Top 10:
|
Company Name |
Symbol |
September Dollar Volume |
|
Roche Holding Ltd. |
$1,707,901,205 |
|
|
Grayscale Bitcoin Trust (BTC) |
$785,442,416 |
|
|
Grayscale Ethereum Trust (ETH) |
$685,952,488 |
|
|
adidas AG |
$317,175,529 |
|
|
BNP Paribas |
$295,090,950 |
|
|
Deutsche Telekom AG |
$268,213,144 |
|
|
Computer Services Inc. |
$216,708,362 |
|
|
Akzo Nobel N.V. |
$167,395,328 |
|
|
Danone |
$167,340,096 |
|
|
Infineon Technologies AG |
$158,503,975 |
OTCQB Top 10:
|
Company Name |
Symbol |
September Dollar Volume |
|
Global Tech Industries Group Inc. |
$119,304,739 |
|
|
Lake Resources N.L. |
$24,528,742 |
|
|
Stemtech Corp. |
$22,459,406 |
|
|
Northwest Biotherapeutics Inc. |
$21,313,034 |
|
|
American Battery Technology Co. |
$16,729,817 |
|
|
Fannie Mae |
$15,086,158 |
|
|
CytoDyn Inc. |
$14,135,987 |
|
|
Netlist Inc. |
$13,413,921 |
|
|
Freddie Mac |
$12,995,635 |
|
|
Know Labs Inc. |
$10,652,167 |
This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice.
Featured photo by Kelly Sikkema on Unsplash
© 2025 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
Trade confidently with insights and alerts from analyst ratings, free reports and breaking news that affects the stocks you care about.
