Largest Study of Medtronic CoreValve System Confirms Positive Clinical Outcomes

Medtronic, Inc. MDT today issued a statement on results from an independent study published online in the journal Circulation, which confirmed both early and sustained clinical benefits for patients receiving the Medtronic CoreValve® System for the treatment of aortic valve disease. The article, “Incidence and Predictors of Early and Late Mortality After Transcatheter Aortic Valve Implantation in 663 Patients With Severe Aortic Stenosis,” discusses the largest CoreValve clinical study to date, with 663 consecutive aortic stenosis patients (mean age of 81 years) treated at 14 Italian centers beginning immediately after device commercialization in 2007. The article shows that patients receiving CoreValve have high rates of procedural success (98 percent), low rates of adverse events (2.1 percent) and substantial improvements of cardiac function.