MAKO Surgical Corp. Expects it Will Sell 56-62 Rio Systems in 2012

MAKO Surgical Corp. MAKO today announced its selected operating results for its fourth quarter and for the year ended December 31, 2011 and provided 2012 annual guidance in anticipation of its business update presentation at the 30th Annual J.P. Morgan Healthcare Conference at the Westin St. Francis Hotel in San Francisco on Wednesday, January 11, 2012 at 7:30 am PST. 2011 Fourth Quarter and Full Year Review RIO Systems – Eighteen RIO systems were sold during the fourth quarter, of which sixteen were sold to domestic customers and two were sold to two new international distributors, which will be used by the distributors to demonstrate MAKOplasty to build interest in their respective markets. A total of 48 new RIO systems were sold worldwide in 2011, bringing MAKO's worldwide commercial installed base of RIO systems to 113 systems and domestic commercial installed base to 111 RIO systems as of December 31, 2011. MAKOplasty Procedure Volume – During the fourth quarter, 2,258 MAKOplasty procedures were performed, of which 2,167 were performed at domestic sites and 117 were Total Hip Arthroplasty (THA) procedures. The 2,258 MAKOplasty procedures performed represent a 25% increase over the procedures performed in the third quarter of 2011 and a 97% increase over the procedures performed in the fourth quarter of 2010. The average monthly utilization per system was 7.2 procedures during the fourth quarter of 2011, an increase from 6.5 procedures per system per month in the third quarter of 2011 and 6.7 procedures per system per month in the fourth quarter of 2010. A total of 6,932 MAKOplasty procedures were performed in 2011, representing a 99% increase over the total procedures performed in 2010. Through December 31, 2011, a total of 12,801 procedures have been performed since the first procedure in June 2006. MAKOplasty Total Hip Arthroplasty – In the fourth quarter, 37 MAKOplasty THA applications were sold, of which nine were sold and installed with RIO systems sold during the fourth quarter. A total of 49 MAKOplasty THA applications were sold in 2011 and as of December 31, 2011, 44% of MAKO's domestic commercial installed base has purchased and received the MAKOplasty THA application. "We are pleased with our strong RIO system sales and the interest in our hip application during the fourth quarter. In addition, we believe the increased MAKOplasty procedure volume and utilization trends continue to demonstrate the clinical value of our technology," said Maurice R. Ferre, M.D., President and Chief Executive Officer of MAKO. "2011 was a positive year for MAKO and we look forward to continuing to drive the adoption of MAKOplasty in 2012." 2012 Annual Guidance MAKO anticipates that it will sell 56 to 62 RIO systems and that its customers will perform 11,000 to 13,000 MAKOplasty procedures in 2012.