Wednesday's morning session saw 49 companies set new 52-week highs.

Areas of Significance:

• The largest company by market cap to hit a new 52-week high was Danaher DHR.
• LifeSci Acquisition LSAC was the smallest Company by market cap to set a new 52-week high.
• CTI BioPharma CTIC was the biggest gainer, trading up 120.95% to reach its 52-week high.

During the first half-hour of trading on Wednesday, the following stocks broke to new 52-week highs:

• Danaher DHR shares hit $212.88 on Wednesday morning, setting a new 52-week high for a change of up 0.39%.
• Dell Technologies DELL shares hit $68.88 on Wednesday morning, setting a new 52-week high for a change of up 0.39%.
• Seattle Genetics SGEN shares achieved a new 52-week high on Wednesday morning, hitting $194.44 with a daily change of up 1.07%.
• Cummins CMI shares hit a new 52-week high of $216.61. The stock traded up 0.93% on the session.
• Lennar LEN shares set a new yearly high of $81.72 this morning. The stock was up 2.21% on the session.
• NIO NIO shares hit a new 52-week high of $22.49. The stock traded up 5.66% on the session.
• Zillow Gr ZG shares hit a new 52-week high of $103.23. The stock traded up 1.13% on the session.
• Zillow Gr Z stock set a new 52-week high of $103.45 Wednesday morning. Over the session, the stock traded up 1.01%.
• BeiGene BGNE shares hit $287.06 on Wednesday morning, setting a new 52-week high for a change of up 1.53%.
• PerkinElmer PKI stock hit a yearly high price of $124.98. The stock was up 1.06% for the day.
• PPD PPD shares set a new yearly high of $36.14 this morning. The stock was up 2.36% on the session.
• SolarEdge Technologies SEDG shares were up 0.22% on Wednesday to hit a new 52-week high of $236.06 for a change of up 0.22%.
• NovoCure NVCR stock hit a yearly high price of $112.34. The stock was up 1.17% for the day.
• Beyond Meat BYND stock made a new 52-week high of $172.45 Wednesday. The stock was up 2.81% for the day.
• James Hardie Industries JHX stock set a new 52-week high of $23.91 Wednesday morning. Over the session, the stock traded up 0.21%.
• Enphase Energy ENPH shares were up 2.41% on Wednesday to hit a new 52-week high of $83.84 for a change of up 2.41%.
• Graco GGG shares broke to a new 52-week high of $62.00 on Wednesday. Shares of the company traded up 0.38%.
• L Brands LB shares hit a new 52-week high of $33.12. The stock traded up 8.35% on the session.
• Sunrun RUN shares set a new 52-week high of $75.69 on Wednesday, moving up 2.31%.
• Paylocity Holding PCTY stock hit a yearly high price of $165.00. The stock was up 1.16% for the day.
• New Fortress Energy NFE shares broke to a new 52-week high of $44.12 on Wednesday. Shares of the company traded up 0.83%.
• Dunkin Brands Group DNKN shares set a new yearly high of $81.92 this morning. The stock was up 0.92% on the session.
• Acceleron Pharma XLRN shares hit a yearly high of $114.32. The stock traded down 0.4% on the session.
• Vivint Solar VSLR stock made a new 52-week high of $41.60 Wednesday. The stock was up 2.43% for the day.
• Blueprint Medicines BPMC shares broke to a new 52-week high of $92.75 on Wednesday. Shares of the company traded up 0.58%.
• Appian APPN shares hit a yearly high of $67.42. The stock traded up 1.16% on the session.
• Advanced Drainage Systems WMS stock made a new 52-week high of $62.74 Wednesday. The stock was up 2.53% for the day.
• Meritage Homes MTH shares reached a new 52-week high of $109.58 on Wednesday morning, moving up 1.61%.
• Endava DAVA stock set a new 52-week high of $62.35 Wednesday morning. Over the session, the stock traded up 1.84%.
• Installed Building Prods IBP stock on Wednesday broke to a yearly high of $103.29. Shares traded up 1.89%.
• Open Lending LPRO shares were up 2.15% on Wednesday morning to hit a new 52-week high of $25.98.
• Dorman Products DORM stock on Wednesday broke to a yearly high of $90.37. Shares traded up 0.88%.
• Trupanion TRUP stock hit a yearly high price of $79.67. The stock was up 0.05% for the day.
• Renewable Energy Group REGI shares set a new 52-week high of $53.61 on Wednesday, moving up 5.3%.
• Canadian Solar CSIQ shares hit $35.18 on Wednesday morning, setting a new 52-week high for a change of up 0.98%.
• JinkoSolar Holding Co JKS stock set a new 52-week high of $40.29 Wednesday morning. Over the session, the stock traded down 0.18%.
• Kura Oncology KURA shares achieved a new 52-week high on Wednesday morning, hitting $31.28 with a daily change of up 1.54%.
• CareDx CDNA shares hit $38.01 on Wednesday morning, setting a new 52-week high for a change of up 1.84%.
• Omega Flex OFLX stock set a new 52-week high of $158.67 Wednesday morning. Over the session, the stock traded up 0.64%.
• Pacific Biosciences PACB shares hit $10.10 on Wednesday morning, setting a new 52-week high for a change of up 2.55%.
• Century Communities CCS shares were up 2.06% on Wednesday to hit a new 52-week high of $41.73 for a change of up 2.06%.
• TechTarget TTGT shares set a new yearly high of $44.89 this morning. The stock was up 2.17% on the session.
• Lithium Americas LAC shares set a new yearly high of $11.54 this morning. The stock was up 5.92% on the session.
• SunOpta STKL shares broke to a new 52-week high of $7.91 on Wednesday. Shares of the company traded up 2.53%.
• BioLife Solutions BLFS shares reached a new 52-week high of $29.49 on Wednesday morning, moving up 2.51%.
• Kaleido Biosciences KLDO shares broke to a new 52-week high of $11.14 on Wednesday. Shares of the company traded up 8.09%.
• Cardiff Oncology CRDF stock made a new 52-week high of $16.00 Wednesday. The stock was up 9.65% for the day.
• CTI BioPharma CTIC shares were up 120.95% on Wednesday to hit a new 52-week high of $2.67 for a change of up 120.95%.
• LifeSci Acquisition LSAC shares set a new 52-week high of $12.76 on Wednesday, moving up 0.79%.

Benzinga will update traders on these companies going forward. If these companies break to a new level, Benzinga will be the first to report on it.