Before 10 a.m. ET on Wednesday, 192 companies set new 52-week highs.

Highlights:

• The largest company by market cap to hit a new 52-week high was Microsoft MSFT.
• Shineco TYHT was the smallest, in terms of market cap, to set a new 52-week high.
• Tyme Technologies TYME's stock rose the most, as it traded up 82.44% to reach a new 52-week high.

Over the course of the first half-hour of trading on Wednesday, the following stocks hit new 52-week highs:

• Microsoft MSFT shares hit a yearly high of $243.40. The stock traded up 1.56% on the session.
• Alphabet GOOG stock on Wednesday broke to a yearly high of $2,093.18. Shares traded up 7.54%.
• Alphabet GOOGL shares set a new yearly high of $2,086.99 this morning. The stock was up 7.49% on the session.
• Pinduoduo PDD shares hit $197.73 on Wednesday morning, setting a new 52-week high for a change of up 7.08%.
• Broadcom AVGO shares were down 1.46% on Wednesday morning to hit a new 52-week high of $478.52.
• Sony SNE shares reached a new 52-week high of $111.60 on Wednesday morning, moving up 10.89%.
• Sea SE shares were up 1.51% on Wednesday to hit a new 52-week high of $245.00 for a change of up 1.51%.
• Snap SNAP shares hit $60.35 on Wednesday morning, setting a new 52-week high for a change of up 0.99%.
• Workday WDAY shares hit a yearly high of $261.62. The stock traded up 1.05% on the session.
• Dell Technologies DELL stock hit a yearly high price of $78.05. The stock was up 0.16% for the day.
• Blackstone Group BX shares hit a yearly high of $71.47. The stock traded down 0.68% on the session.
• RingCentral RNG shares achieved a new 52-week high on Wednesday morning, hitting $405.47 with a daily change of down 1.18%.
• MongoDB MDB shares set a new yearly high of $419.94 this morning. The stock was up 0.71% on the session.
• Farfetch FTCH shares broke to a new 52-week high of $68.44 on Wednesday. Shares of the company traded up 5.92%.
• Vipshop Holdings VIPS stock hit a yearly high price of $32.24. The stock was up 1.82% for the day.
• EPAM Systems EPAM stock set a new 52-week high of $373.02 Wednesday morning. Over the session, the stock traded up 0.04%.
• CNH Industrial CNHI shares were up 0.87% for the day, having made a 52-week high of $14.15.
• Futu Holdings FUTU shares hit a new 52-week high of $132.95. The stock traded up 12.34% on the session.
• Tata Motors TTM shares broke to a new 52-week high of $22.60 on Wednesday. Shares of the company traded up 0.38%.
• Penn National Gaming PENN shares broke to $113.17 on Wednesday, setting a new 52-week high with a change of down 1.05%.
• argenx ARGX shares broke to a new 52-week high of $370.80 on Wednesday. Shares of the company traded up 9.05%.
• Canopy Gwth CGC shares were up 6.41% on Wednesday morning to hit a new 52-week high of $45.06.
• Raymond James Financial RJF stock on Wednesday broke to a yearly high of $106.00. Shares traded up 0.78%.
• Dynatrace DT shares broke to $52.48 on Wednesday, setting a new 52-week high with a change of up 12.7%.
• Avery Dennison AVY shares broke to a new 52-week high of $167.95 on Wednesday. Shares of the company traded up 6.35%.
• Scotts Miracle Gro SMG shares set a new yearly high of $250.00 this morning. The stock was up 5.86% on the session.
• Kingsoft Cloud Holdings KC shares hit $62.24 on Wednesday morning, setting a new 52-week high for a change of up 0.97%.
• Anaplan PLAN shares achieved a new 52-week high on Wednesday morning, hitting $76.69 with a daily change of up 2.22%.
• Interpublic Gr of Cos IPG shares set a new 52-week high of $25.72 on Wednesday, moving up 1.53%.
• Amdocs DOX shares hit $77.44 on Wednesday morning, setting a new 52-week high for a change of up 2.59%.
• Signature Bank SBNY shares broke to $179.20 on Wednesday, setting a new 52-week high with a change of down 0.78%.
• East West Bancorp EWBC shares achieved a new 52-week high on Wednesday morning, hitting $63.89 with a daily change of down 0.11%.
• JOYY YY stock made a new 52-week high of $109.68 Wednesday. The stock was up 5.91% for the day.
• Agora API shares hit a yearly high of $84.95. The stock traded up 12.5% on the session.
• eXp World Holdings EXPI shares hit a yearly high of $122.89. The stock traded down 1.7% on the session.
• Manhattan Associates MANH shares set a new 52-week high of $132.35 on Wednesday, moving up 3.76%.
• Atea Pharmaceuticals AVIR shares hit $89.44 on Wednesday morning, setting a new 52-week high for a change of up 6.7%.
• 1Life Healthcare ONEM shares achieved a new 52-week high on Wednesday morning, hitting $55.47 with a daily change of down 0.44%.
• R1 RCM RCM shares were down 2.21% on Wednesday morning to hit a new 52-week high of $27.53.
• MicroStrategy MSTR shares broke to a new 52-week high of $750.80 on Wednesday. Shares of the company traded up 4.15%.
• Pure Storage PSTG shares were up 1.09% for the day, having made a 52-week high of $25.53.
• GW Pharmaceuticals GWPH shares set a new 52-week high of $217.50 on Wednesday, moving up 46.27%.
• Halozyme Therapeutics HALO stock set a new 52-week high of $50.31 Wednesday morning. Over the session, the stock traded down 2.37%.
• Synovus Finl SNV shares were up 0.15% on Wednesday to hit a new 52-week high of $39.68 for a change of up 0.15%.
• Varonis Systems VRNS shares achieved a new 52-week high on Wednesday morning, hitting $191.31 with a daily change of down 3.3%.
• Upwork UPWK shares reached a new 52-week high of $49.22 on Wednesday morning, moving up 0.51%.
• Upstart Holdings UPST shares reached a new 52-week high of $81.89 on Wednesday morning, moving up 5.43%.
• SLM SLM shares achieved a new 52-week high on Wednesday morning, hitting $15.32 with a daily change of up 1.19%.
• 3D Sys DDD shares were up 14.17% for the day, having made a 52-week high of $45.32.
• Aphria APHA shares set a new 52-week high of $17.50 on Wednesday, moving up 15.2%.
• Open Lending LPRO shares were up 3.55% for the day, having made a 52-week high of $41.86.
• Staar Surgical STAA shares reached a new 52-week high of $111.68 on Wednesday morning, moving up 0.24%.
• Evercore EVR shares set a new 52-week high of $126.58 on Wednesday, moving up 6.0%.
• Innovative Industrial IIPR stock made a new 52-week high of $209.58 Wednesday. The stock was up 0.63% for the day.
• Magnite MGNI stock hit a yearly high price of $42.20. The stock was up 3.38% for the day.
• I-MAB IMAB stock on Wednesday broke to a yearly high of $65.54. Shares traded down 0.75%.
• Yalla Group YALA shares hit a new 52-week high of $31.87. The stock traded up 6.21% on the session.
• Cronos Group CRON shares hit $12.75 on Wednesday morning, setting a new 52-week high for a change of up 10.22%.
• PagerDuty PD shares achieved a new 52-week high on Wednesday morning, hitting $54.57 with a daily change of down 0.85%.
• Tilray TLRY shares hit a yearly high of $28.86. The stock traded up 14.92% on the session.
• Veracyte VCYT stock on Wednesday broke to a yearly high of $76.64. Shares traded up 12.66%.
• Option Care Health OPCH stock set a new 52-week high of $20.73 Wednesday morning. Over the session, the stock traded up 4.41%.
• Viavi Solutions VIAV shares were up 2.68% on Wednesday to hit a new 52-week high of $17.01 for a change of up 2.68%.
• Colliers Intl Gr CIGI shares broke to a new 52-week high of $95.01 on Wednesday. Shares of the company traded down 1.03%.
• Sonos SONO shares set a new yearly high of $30.49 this morning. The stock was up 4.85% on the session.
• UP Fintech Holding TIGR shares hit a yearly high of $24.65. The stock traded up 18.01% on the session.
• Tower Semiconductor TSEM shares hit a yearly high of $31.12. The stock traded down 0.91% on the session.
• Sunoco SUN shares were up 1.19% on Wednesday to hit a new 52-week high of $32.65 for a change of up 1.19%.
• Veoneer VNE shares broke to $29.54 on Wednesday, setting a new 52-week high with a change of up 5.68%.
• Investors Bancorp ISBC shares broke to $12.98 on Wednesday, setting a new 52-week high with a change of up 6.48%.
• GrowGeneration GRWG shares were up 3.94% on Wednesday to hit a new 52-week high of $55.19 for a change of up 3.94%.
• St. Joe JOE shares reached a new 52-week high of $50.66 on Wednesday morning, moving down 1.62%.
• Onto Innovation ONTO shares set a new yearly high of $60.59 this morning. The stock was down 2.34% on the session.
• 360 DigiTech QFIN shares were down 2.45% for the day, having made a 52-week high of $19.60.
• Stratasys SSYS shares set a new yearly high of $51.29 this morning. The stock was up 5.12% on the session.
• Intra-Cellular Therapies ITCI stock set a new 52-week high of $35.16 Wednesday morning. Over the session, the stock traded up 1.32%.
• Primo Water PRMW shares hit a new 52-week high of $16.75. The stock traded up 0.85% on the session.
• Arcus Biosciences RCUS stock hit a yearly high price of $41.13. The stock was up 2.89% for the day.
• Calamos Strategic Total CSQ shares hit a yearly high of $16.20. The stock traded up 0.12% on the session.
• Clean Energy Fuels CLNE shares were up 17.48% on Wednesday to hit a new 52-week high of $13.10 for a change of up 17.48%.
• Silvergate Capital SI shares set a new yearly high of $113.58 this morning. The stock was down 1.85% on the session.
• Myriad Genetics MYGN stock made a new 52-week high of $31.00 Wednesday. The stock was up 1.59% for the day.
• Meritor MTOR stock set a new 52-week high of $32.97 Wednesday morning. Over the session, the stock traded up 15.61%.
• Skyline Champion SKY shares were down 1.72% on Wednesday to hit a new 52-week high of $41.29 for a change of down 1.72%.
• NantKwest NK shares broke to $21.01 on Wednesday, setting a new 52-week high with a change of down 4.93%.
• Adtalem Glb Education ATGE shares set a new 52-week high of $43.85 on Wednesday, moving up 1.74%.
• InMode INMD shares hit a yearly high of $66.11. The stock traded up 1.39% on the session.
• Castle Biosciences CSTL shares hit a new 52-week high of $86.58. The stock traded up 0.93% on the session.
• Perficient PRFT shares were down 1.67% on Wednesday to hit a new 52-week high of $59.32 for a change of down 1.67%.
• Knowles KN shares broke to a new 52-week high of $20.59 on Wednesday. Shares of the company traded up 1.04%.
• Silicon Motion Technology SIMO stock hit a yearly high price of $53.02. The stock was up 0.32% for the day.
• C4 Therapeutics CCCC shares achieved a new 52-week high on Wednesday morning, hitting $45.20 with a daily change of up 1.22%.
• Vista Outdoor VSTO shares hit a new 52-week high of $31.97. The stock traded down 0.77% on the session.
• Codexis CDXS shares were up 0.04% for the day, having made a 52-week high of $28.80.
• Frequency Therapeutics FREQ shares hit $50.00 on Wednesday morning, setting a new 52-week high for a change of up 4.83%.
• Talend TLND shares set a new 52-week high of $50.83 on Wednesday, moving down 1.5%.
• Organogenesis Holdings ORGO shares reached a new 52-week high of $11.94 on Wednesday morning, moving up 0.06%.
• Plantronics PLT shares hit a new 52-week high of $35.58. The stock traded up 2.92% on the session.
• Mission Produce AVO stock made a new 52-week high of $20.45 Wednesday. The stock was up 3.71% for the day.
• Blackrock Credit BTZ shares reached a new 52-week high of $15.14 on Wednesday morning, moving up 1.44%.
• SunOpta STKL shares hit a yearly high of $16.00. The stock traded 0.0% (flat) on the session.
• BlackRock Science BST shares broke to a new 52-week high of $56.95 on Wednesday. Shares of the company traded up 0.48%.
• FTAC Olympus Acquisition FTOC shares broke to $14.42 on Wednesday, setting a new 52-week high with a change of up 9.07%.
• Meta Financial Group CASH shares broke to $41.51 on Wednesday, setting a new 52-week high with a change of down 0.49%.
• Nexgen Energy Ltd. Common Shares NXE shares hit $3.32 on Wednesday morning, setting a new 52-week high for a change of up 3.79%.
• Morphic Holding MORF stock made a new 52-week high of $38.89 Wednesday. The stock was up 5.36% for the day.
• Alphatec Holdings ATEC stock made a new 52-week high of $15.99 Wednesday. The stock was down 2.56% for the day.
• CC Neuberger Principal PRPB shares hit $10.97 on Wednesday morning, setting a new 52-week high for a change of up 1.97%.
• Ribbon Comms RBBN shares broke to a new 52-week high of $8.37 on Wednesday. Shares of the company traded down 0.86%.
• QuinStreet QNST shares broke to a new 52-week high of $23.32 on Wednesday. Shares of the company traded up 0.73%.
• FinVolution Gr FINV shares achieved a new 52-week high on Wednesday morning, hitting $4.17 with a daily change of up 5.33%.
• Dragoneer Growth Opp DGNR shares achieved a new 52-week high on Wednesday morning, hitting $16.11 with a daily change of down 3.85%.
• The Shyft Group SHYF shares achieved a new 52-week high on Wednesday morning, hitting $33.11 with a daily change of down 0.94%.
• Columbus McKinnon CMCO shares reached a new 52-week high of $46.80 on Wednesday morning, moving down 0.99%.
• Calamos Convertible CHY shares were up 0.48% on Wednesday to hit a new 52-week high of $15.13 for a change of up 0.48%.
• MannKind MNKD shares reached a new 52-week high of $4.93 on Wednesday morning, moving up 20.83%.
• The Bancorp TBBK stock set a new 52-week high of $18.93 Wednesday morning. Over the session, the stock traded down 1.53%.
• Premier Financial PFC shares hit a new 52-week high of $28.65. The stock traded down 2.78% on the session.
• Cornerstone Strategic Value Fund, Inc. New Common Stock CLM stock hit a yearly high price of $13.50. The stock was up 1.93% for the day.
• CALAMOS CONVERTIBLE CHI shares hit $14.32 on Wednesday morning, setting a new 52-week high for a change of up 0.21%.
• Arcimoto FUV shares were up 12.93% for the day, having made a 52-week high of $30.89.
• HEXO HEXO shares achieved a new 52-week high on Wednesday morning, hitting $8.17 with a daily change of up 11.67%.
• Boston Omaha BOMN stock made a new 52-week high of $36.20 Wednesday. The stock was up 1.17% for the day.
• Avid Technology AVID shares set a new 52-week high of $20.25 on Wednesday, moving up 4.42%.
• Altus Midstream ALTM stock made a new 52-week high of $54.38 Wednesday. The stock was up 3.13% for the day.
• Alpha & Omega AOSL shares reached a new 52-week high of $35.01 on Wednesday morning, moving up 0.44%.
• Container Store Group TCS shares were up 10.46% on Wednesday morning to hit a new 52-week high of $17.17.
• Mohawk Gr Hldgs MWK shares reached a new 52-week high of $33.30 on Wednesday morning, moving up 8.58%.
• CM Life Sciences CMLF shares set a new 52-week high of $14.99 on Wednesday, moving up 4.72%.
• Calamos Dynamic CCD shares were up 0.5% on Wednesday to hit a new 52-week high of $30.64 for a change of up 0.5%.
• Chuy's Holdings CHUY shares hit a yearly high of $37.35. The stock traded up 3.13% on the session.
• OptimizeRx OPRX stock made a new 52-week high of $49.23 Wednesday. The stock was up 2.27% for the day.
• ExOne XONE shares reached a new 52-week high of $36.98 on Wednesday morning, moving up 8.35%.
• Resolute Forest Products RFP shares hit a yearly high of $8.96. The stock traded up 1.03% on the session.
• Holicity HOL shares were up 2.85% for the day, having made a 52-week high of $17.60.
• Anavex Life Sciences AVXL shares reached a new 52-week high of $10.98 on Wednesday morning, moving up 18.19%.
• Blackrock Muni Interm MUI shares set a new yearly high of $15.10 this morning. The stock was 0.0% (flat) on the session.
• Blackrock Muniholdings MFL shares broke to a new 52-week high of $14.68 on Wednesday. Shares of the company traded up 0.55%.
• VYNE Therapeutics VYNE shares were up 11.03% on Wednesday to hit a new 52-week high of $3.00 for a change of up 11.03%.
• Selecta Biosciences SELB shares broke to $5.70 on Wednesday, setting a new 52-week high with a change of up 13.43%.
• Cornerstone Total Return Fund, Inc. (The) Common Stock CRF shares broke to $13.24 on Wednesday, setting a new 52-week high with a change of up 1.53%.
• Alussa Energy Acquisition ALUS stock set a new 52-week high of $15.28 Wednesday morning. Over the session, the stock traded up 13.35%.
• Jounce Therapeutics JNCE shares set a new 52-week high of $13.22 on Wednesday, moving up 1.01%.
• Rekor Systems REKR shares were up 18.82% on Wednesday to hit a new 52-week high of $14.75 for a change of up 18.82%.
• Cormedix CRMD stock set a new 52-week high of $15.50 Wednesday morning. Over the session, the stock traded up 21.07%.
• D8 Holdings DEH shares hit a yearly high of $10.51. The stock traded up 0.57% on the session.
• Tyme Technologies TYME shares broke to a new 52-week high of $4.99 on Wednesday. Shares of the company traded up 82.44%.
• IDT IDT shares hit a yearly high of $16.35. The stock traded up 4.86% on the session.
• CITIC Capital Acquisition CCAC shares achieved a new 52-week high on Wednesday morning, hitting $11.43 with a daily change of up 3.35%.
• BlueLinx Hldgs BXC stock made a new 52-week high of $39.80 Wednesday. The stock was up 1.95% for the day.
• Remark Holdings MARK shares set a new 52-week high of $3.69 on Wednesday, moving up 10.09%.
• Atlantic Avenue ASAQ stock on Wednesday broke to a yearly high of $10.65. Shares traded up 0.38%.
• Acacia Research ACTG shares reached a new 52-week high of $7.00 on Wednesday morning, moving up 6.07%.
• Net 1 UEPS Technologies UEPS stock hit a yearly high price of $5.86. The stock was up 3.6% for the day.
• Big 5 Sporting Goods BGFV shares were up 3.93% for the day, having made a 52-week high of $14.81.
• Marrone Bio Innovations MBII shares hit $1.99 on Wednesday morning, setting a new 52-week high for a change of up 5.78%.
• Lionheart Acquisition LCAP stock on Wednesday broke to a yearly high of $11.20. Shares traded up 0.82%.
• One AONE shares were up 4.95% on Wednesday morning to hit a new 52-week high of $11.66.
• Morgan Stanley India IIF stock set a new 52-week high of $22.89 Wednesday morning. Over the session, the stock traded up 0.59%.
• Transcat TRNS shares broke to a new 52-week high of $40.15 on Wednesday. Shares of the company traded up 5.14%.
• Sequans Communications SQNS shares set a new yearly high of $8.68 this morning. The stock was up 1.29% on the session.
• Atento ATTO shares achieved a new 52-week high on Wednesday morning, hitting $20.69 with a daily change of up 1.96%.
• Genasys GNSS shares broke to $8.30 on Wednesday, setting a new 52-week high with a change of down 0.12%.
• Oramed Pharmaceuticals ORMP shares hit a yearly high of $10.85. The stock traded up 7.64% on the session.
• KVH Industries KVHI shares hit $14.50 on Wednesday morning, setting a new 52-week high for a change of up 0.85%.
• Aviat Networks AVNW shares hit a yearly high of $45.41. The stock traded down 1.74% on the session.
• Immunome IMNM shares were up 5.26% for the day, having made a 52-week high of $22.89.
• cbdMD, Inc. Common Stock YCBD stock on Wednesday broke to a yearly high of $4.40. Shares traded up 2.16%.
• HyreCar HYRE stock made a new 52-week high of $12.48 Wednesday. The stock was up 3.64% for the day.
• Gabelli Multimedia Trust GGT shares reached a new 52-week high of $8.60 on Wednesday morning, moving up 0.71%.
• Ellsworth Growth and Income Fund Ltd. ECF shares hit a new 52-week high of $16.36. The stock traded down 0.19% on the session.
• RigNet RNET stock hit a yearly high price of $8.78. The stock was up 4.43% for the day.
• AllianzGI Convertible CBH stock set a new 52-week high of $10.12 Wednesday morning. Over the session, the stock traded down 1.84%.
• VAALCO Energy EGY shares reached a new 52-week high of $2.80 on Wednesday morning, moving up 6.23%.
• Qumu QUMU stock hit a yearly high price of $9.59. The stock was up 4.4% for the day.
• Ocuphire Pharma OCUP shares were up 7.94% for the day, having made a 52-week high of $13.62.
• Usio USIO shares were up 16.77% on Wednesday morning to hit a new 52-week high of $5.98.
• ClearSign Technologies CLIR shares broke to a new 52-week high of $4.60 on Wednesday. Shares of the company traded up 12.91%.
• Annovis Bio, Inc. Common Stock ANVS shares broke to a new 52-week high of $18.61 on Wednesday. Shares of the company traded up 8.55%.
• GABELLI CONVERTIBLE GCV shares hit a new 52-week high of $6.56. The stock traded up 0.46% on the session.
• Huttig Building Products HBP shares reached a new 52-week high of $3.98 on Wednesday morning, moving up 2.49%.
• KLX Energy Services Hldgs KLXE shares were up 4.05% for the day, having made a 52-week high of $11.20.
• Coda Octopus Group CODA stock set a new 52-week high of $8.49 Wednesday morning. Over the session, the stock traded up 2.21%.
• Nicholas Financial NICK shares broke to a new 52-week high of $10.49 on Wednesday. Shares of the company traded up 14.46%.
• Ideal Power IPWR shares set a new yearly high of $24.88 this morning. The stock was up 39.42% on the session.
• ZK International Group Co ZKIN shares hit a yearly high of $4.67. The stock traded up 15.85% on the session.
• Charles & Colvard CTHR shares hit a new 52-week high of $2.50. The stock traded up 7.86% on the session.
• Sino-Global Shipping SINO shares broke to a new 52-week high of $11.30 on Wednesday. Shares of the company traded up 59.28%.
• RCM Technologies RCMT stock set a new 52-week high of $3.29 Wednesday morning. Over the session, the stock traded down 2.92%.
• InMed Pharmaceuticals INM shares hit $6.42 on Wednesday morning, setting a new 52-week high for a change of up 17.79%.
• TSR TSRI shares set a new yearly high of $9.48 this morning. The stock was down 6.25% on the session.
• Shineco TYHT stock on Wednesday broke to a yearly high of $4.37. Shares traded up 8.24%.

Benzinga will continue to update traders about these equities going forward. Stay tuned for further market updates.