U.S. stocks traded mostly higher, with the Dow Jones index gaining around 80 points on Wednesday.

Shares of Iovance Biotherapeutics, Inc. IOVA fell sharply during Wednesday’s session after the company announced a clinical program update for LN-145 TIL therapy in non-small lung cancer (NSCLC).

The FDA placed a clinical hold on the IOV-LUN-202 trial on December 22, 2023, in response to a recently reported Grade 5 (fatal) serious adverse event potentially related to the non-myeloablative lymphodepletion pre-conditioning regimen.
Iovance Biotherapeutics shares dipped 20.4% to $7.07 on Wednesday.

Here are some other big stocks recording gains in today’s session.

  • Nukkleus Inc. NUKK shares declined 28.8% to $2.60 after jumping around 11% on Tuesday.
  • GreenTree Hospitality Group Ltd. GHG fell 10% to $3.69.
  • InnSuites Hospitality Trust IHT dipped 8.6% to $1.4250.
  • LanzaTech Global, Inc. LNZA fell 7.6% to $5.00.
  • Life Time Group Holdings, Inc. LTH fell 6.9% to $14.30. On Dec 22, Life Time Group Holdings agreed with company’s CFO, Robert Houghton that he will resign as CFO.
  • Cheche Group Inc. CCG fell 6.3% to $6.51.
  • Canopy Growth Corporation CGC declined 6.2% to $5.31.
  • Velocity Financial, Inc. VEL fell 4.8% to $15.62.
  • The Beauty Health Company SKIN fell 4.8% to $3.0850.
  • NetEase, Inc. NTES fell 4.2% to $88.30 on continued volatility amid regulatory developments in China's gaming sector.
  • NIO Inc. NIO fell 4.1% to $8.95 after rising more than 10% on Tuesday. Nio stock raced higher to start the week after the company launched its new ET9 sedan at its Nio Day event over the weekend.

 

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