Why Applied Therapeutics Shares Are Trading Lower By Over 35%? Here Are Other Stocks Moving In Friday's Mid-Day Session

Shares of Applied Therapeutics, Inc. APLT shares fell sharply during Friday’s session after the company released topline results of the ARISE-HF Phase 3 trial of AT-001 (caficrestat) in patients with Diabetic Cardiomyopathy (DbCM) at high risk of progression to overt heart failure.

The study's primary endpoint was stabilization or improvement in cardiac functional capacity as measured by Peak VO2 in patients treated with AT-001 1500mg twice daily (BID) compared to placebo.

Applied Therapeutics shares dipped 35.6% to $2.4498 on Friday.

Here are some other stocks moving in today's mid-day session.

Gainers

• Ainos, Inc.AIMD jumped 112.6% to $3.6805 after falling more than 12% on Thursday.
• Revelstone Capital Acquisition Corp. RCAC shares climbed 89.6% to $10.71. Revelstone Capital Acquisition cancelled special meeting to approve business combination with Set Jet, Inc.
• Banzai International, Inc. BNZI surged 74% to $2.92. Banzai International signed a non-binding letter of intent to acquire IGLeads, a cutting-edge automated lead generation platform.
• Safe and Green Development Corporation SGD shares rose 56.5% to $2.1307. Safe And Green Development recently issued an update on LOI for acquisition of Xene AI Software platform.
• NexImmune, Inc. NEXI gained 30% to $7.67
• Dermata Therapeutics, Inc. DRMA rose climbed 27.8% to $0.78 after the company announced the issuance of a new patent in Japan for its DMT410 program for the treatment of hyperhidrosis.
• Polished.com Inc. POL gained 27.2% to $8.05.
• Swvl Holdings Corp. SWVL gained 27.2% to $2.90.
• PolyPid Ltd. PYPD gained 25% to $8.44. PolyPid announced $16.2 million private placement of 3,371,312 shares at $4.81 per share.
• AxoGen, Inc. AXGN jumped 20.4% to $8.13 as the company reported preliminary unaudited revenue for fourth quarter and full-year 2023. The company also said President and Chief Executive Officer Karen Zaderej plans to retire from the Company by Jan. 2025.
• Aurora Mobile Limited JG jumped 19.2% to $3.79.
• Kura Sushi USA, Inc. KRUS rose 15.7% to $86.31 following first-quarter results.
• The Greenbrier Companies, Inc. GBX gained 13.8% to $50.50 following upbeat earnings.
• Peloton Interactive, Inc. PTON rose 13.1% to $6.93.
• Pinstripes Holdings Inc. PNST shares gained 12.4% to $5.92 after dipping over 35% on Thursday.
• Cyclacel Pharmaceuticals, Inc. CYCC rose 12.4% to $2.53.
• Elanco Animal Health Incorporated ELAN gained 8% to $15.72. Stifel analyst Jonathan Block upgraded Elanco Animal Health from Hold to Buy and raised the price target from $13 to $20.
• Intelligent Bio Solutions Inc. INBS shares rose 7.2% to $0.3212 after falling around 5% on Thursday. Intelligent Bio Solutions recently received National Association of Testing Authorities accreditation for its Intelligent Fingerprinting Drug Screening Solution.

Losers

• agilon health, inc. AGL tumbled 35.1% to $7.84 after the company lowered its 2023 financial outlook.
• Avenue Therapeutics, Inc. ATXI shares fell 33.7% to $0.2266. Avenue Therapeutics shares jumped over 94% on Thursday after the company announced it reached a final agreement with the FDA for the Phase 3 safety study for IV tramadol.
• Medical Properties Trust, Inc. MPW fell 30.6% to $3.4699 after it disclosed plans to reduce its exposure to tenant Steward Health Care System. Keybanc analyst Austin Wurschmidt downgraded Medical Properties Trust from Overweight to Sector Weight.
• AngioDynamics, Inc. ANGO dipped 22.6% to $6.00 after the company lowered its FY24 guidance.
• Lucy Scientific Discovery Inc. LSDI fell 22% to $0.1949.
• Voyager Therapeutics, Inc. VYGR fell 19.1% to $8.77. Voyager Therapeutics priced its public offering of 7,777,778 common shares at $9 per share.
• Verb Technology Company, Inc. VERB shares fell 17.4% to $0.1340. On Dec. 29, Verb Technology Company entered into a securities purchase agreement with Streeterville Capital where company sold and investor purchased 3,000 shares of the company's newly designated non-convertible Series C preferred stock for $3 million.
• KORE Group Holdings, Inc. KORE shares fell 14.8% to $1.04 after jumping over 60% on Thursday.
• Allogene Therapeutics, Inc. ALLO shares declined 14.1% to $2.9050. Allogene Therapeutics and Foresight Diagnostics disclosed a partnership to develop MRD-based in-vitro diagnostic for use in ALPHA3, the first pivotal trial for frontline consolidation in large B-cell lymphoma. JMP Securities and Guggenheim downgraded the stock.
• Omega Therapeutics, Inc. OMGA declined 13.8% to $4.58.
• CISO Global Inc. CISO shares fell 13.7% to $0.0901. CISO Global said the Nasdaq has determined to delist securities from Nasdaq.
• Catalyst Pharmaceuticals, Inc. CPRX shares fell 13.4% to $14.81 after announcing pricing of public offering of common stock.
• Smart for Life, Inc. SMFL shares fell 12.3% to $1.6408 after jumping around 15% on Thursday.
• Exscientia plc EXAI fell 10.8% to $5.84. B of A Securities analyst Michael Ryskin downgraded Exscientia from Buy to Neutral and lowered the price target from $11 to $9.
• SAB Biotherapeutics, Inc. SABS tumbled 9.1% to $5.90.
• Sabine Royalty Trust SBR fell 8.7% to $63.02.
• Dyne Therapeutics, Inc. DYN shares fell 8% to $17.84. Dyne Therapeutics priced its $300 million public offering of 17.15 million common stock at $17.50 per share.
• Immunocore Holdings plc IMCR dipped 7.3% to $64.61. Immunocore announced strategic priorities and pipeline expansion ahead of 42nd Annual J.P. Morgan Healthcare Conference presentation.
• Theravance Biopharma, Inc. TBPH shares fell 6.6% to $10.76 after the company announced results from Phase 4 YUPELRI PIFR-2 study. The company said study did not show a statistically significant difference between yupelri and spiriva handihaler on primary endpoint.

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