Dow Turns Lower; Tempest Therapeutics Shares Spike Higher

U.S. stocks traded mixed midway through trading, with the Dow Jones falling more than 50 points on Wednesday.

The Dow traded down 0.19% to 33,674.66 while the NASDAQ rose 0.18% to 13,586.67. The S&P 500 also rose, gaining, 0.12% to 4,353.19.

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Leading and Lagging Sectors

 

Real estate shares surged by 0.9% on Wednesday.

In trading on Wednesday, energy shares fell by 1.9%.

 

Top Headline

 

Producer prices in the U.S. increased 0.5% month-over-month in September, versus a 0.7% rise in the prior month, but above market expectations of 0.3%.

 

Equities Trading UP

 

Tempest Therapeutics, Inc. TPST shares shot up 1942% to $4.90 after the company released new data demonstrating superiority of TPST-1120 arm across multiple study endpoints in first-line hepatocellular carcinoma study.

Shares of Phio Pharmaceuticals Corp. PHIO got a boost, shooting 59% to $2.16 after the company announced the poster presentation of two key preclinical studies of its INTASYL compound PH-894 at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics.

voxeljet AG VJET shares were also up, gaining 24% to $1.2780 after the company announced it was selected for a $14.9 million contract alongside GE Research to develop advanced manufacturing technologies to enable the U.S. energy transition.

 

Equities Trading DOWN

 

Silk Road Medical, Inc SILK shares dropped 52% to $6.76 after the company announced preliminary third-quarter revenue results below estimates and issued FY23 revenue guidance below estimates.

Shares of E2open Parent Holdings, Inc. ETWO were down 46% to $2.3750 as the company posted downbeat results for its second quarter and named Andrew Appel as interim CEO, effective immediately.

Hyliion Holdings Corp. HYLN was down, falling 48% to $0.6164. The company late Tuesday said it is exploring strategic options for its powertrain business due to the evolving commercial vehicle electrification industry, slow market adoption and the need for continued investment and regulatory compliance.

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Commodities

 

In commodity news, oil traded down 2% to $84.24 while gold traded up 0.8% at $1,889.60.

Silver traded up 1.1% to $22.19 on Wednesday while copper fell 0.5% to $3.6150.

 

Euro zone

 

European shares were mostly higher today. The eurozone’s STOXX 600 gained 0.15% London’s FTSE 100 fell 0.11% while Spain’s IBEX 35 Index rose 0.09% The German DAX rose 0.24% French CAC 40 slipped 0.44%, while Italy’s FTSE MIB Index gained 0.36%.

Germany’s consumer price inflation rate fell to 4.5% year-over-year in September from 6.1% in the prior month.

 

Asia Pacific Markets

 

Asian markets closed higher on Wednesday, with Japan’s Nikkei 225 gaining 0.60%, China’s Shanghai Composite Index gaining 0.12% and Hong Kong’s Hang Seng Index gaining 1.29%. India’s S&P BSE Sensex, meanwhile, rose 0.6%.

Chinese vehicle sales climbed by 9.5% year-over-year in September, recording the second straight month of growth. Japan's machine tool orders fell 11.2% year-over-year to JPY 133,913 million in September following a 17.6% decline in the prior month, while Reuters Tankan sentiment index for manufacturers in Japan was unchanged at +4 for October.

 

Economics

 

Mortgage applications in the U.S. rose by 0.6% in the week ending Oct. 6..

Producer prices in the U.S. increased 0.5% month-over-month in September, versus a 0.7% rise in the prior month, but above market expectations of 0.3%.

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