Top Percentage Gainers and Losers as of 12pm 06/10/11

Best 1) Coffee Holding JVA: Trading up 26.4% from yesterday's close to $15.21. A positive article regarding Coffee Holding was published by TheStreet.com after the bell Thursday night. The stock has gained 115% over the past five trading sessions. Shares set a 52-week high of $15.50 in the session.

2) Chelsea Therapeutics International CHTP: Trading up 16% from yesterday's close to $4.87. The price target for shares of Chelsea was raised from $6 to $18 at Roth Capital. Yesterday, the company announced positive Phase III results for its neurology drug Northera.

3) Micromet MITI: Trading up 13.8% from yesterday's close to $6.01. Micromet announced positive results for its acute lymphoblastic leukemia treatment blinatumomab. 4) Yongye International YONG: Trading up 13.4% from yesterday's close to $4.82. Last night, Yongye announced the closing of the $50 million equity investment by Morgan Stanley Private Equity Asia. 5) Yuhe International YUII: Trading up 12.7% from yesterday's close to $4.36. Shares of Yuhe set a 52-week low of $3.87 in yesterday's trading session. Other Notable Gainers Verigy VRGY: Trading up 10.9% from yesterday's close to $14.95. Verigy announced that Advantest ATE has gained approval from regulators to acquire the company for $15 per share. LML Payment Systems LMLP: Trading up 10.6% from yesterday's close to $3.13. Identive Group INVE: Trading up $6.8% from yesterday's close to $2.37. Worst 1) RealD RLD: Trading down 14.4% from yesterday's close to $20.60. Shares of RealD are experienced the biggest intraday loss since their IPO in July, as analysts question how lucrative the 3-D movie business will be. The stock has lost 42% in the past 16 trading sessions. 2) Diodes DIOD: Trading down 13.5% from yesterday's close to $23.67. The company lowered its gross margin guidance to 32.5 percent (plus or minus 1.5 percent). Diodes says the margin is being negatively impacted by shrinking demand and a slower-than-expected recovery from recent manpower shortages at company packing facilities in China. 3) Life Partners Holdings LPHI: Trading down 13.5% from yesterday's close to $3.26. Life Partners announced that its auditor, Ernst & Young, resigned last week. 4) Zale ZLC: Trading down 13.4% from yesterday's close to $5.42. Zale was cut from Buy to Neutral by Bank of America BAC. Shares of Zale recently set a 52-week high of $6.81 on June 8th. 5) ChinaCache International Holdings CCIH: Trading down 11.9% from yesterday's close to $6.85. Shares of ChinaCache hit a 52-week low of $6.80 in today's session. The year-to-date performance of ChinaCache has been a loss of 67%. Other Notable Losers China Natural Gas CHNG: Trading down 11.9% from yesterday's close to $2.44. Cooper Tire & Rubber CTB: Trading down 7.8% from yesterday's close to $19.59. Amarin Corporation AMRN: Trading down 7.4% from yesterday's close to $15.10.