- Mast Therapeutics Inc MSTX shares tumbled 80.3 percent to $0.116 after the company announced its phase-3 EPIC trial of vepoloxamer for the treatment of sickle cell disease patients experiencing vaso-occlusive crisis failed to meet its primary efficacy endpoint.
- Mirna Therapeutics Inc MIRN shares fell 23.7 percent to $1.88 as the company disclosed that it has decided to close the Phase 1 clinical study of MRX34. Oppenheimer downgraded Mirna Therapeutics from Outperform to Perform.
- CareDx Inc CDNA declined 11.6 percent to $3.80. CareDx priced its 2.25 million share offering at $4 per share.
- Sorl Auto Parts, Inc. SORL shares fell 10.7 percent to $3.86. Greenridge Global downgraded SORL Auto from Buy to Hold
- Skechers USA Inc SKX shares dropped 9.5 percent to $21.02. Morgan Stanley downgraded Skechers USA from Overweight to Equal-weight and lowered the price target from $41.00 to $25.00.
- Pacira Pharmaceuticals Inc PCRX shares slipped 9.2 percent to $36.67. Pacira Pharmaceuticals shares have dropped 36.39 percent over the past 52 weeks, while the S&P 500 index has gained 8.78 percent in the same period.
- West Pharmaceutical Services Inc. WST dropped 7.9 percent to $74.91. Wells Fargo downgraded West Pharmaceutical from Outperform to Market Perform.
- La Jolla Pharmaceutical Company LJPC shares declined 7.4 percent to $25.02. La Jolla Pharmaceutical shares have declined 29.19 percent over the past 52 weeks, while the S&P 500 index has gained 8.78 percent in the same period.
- Airgain Inc AIRG dropped 5.9 percent to $15.17. Airgain reported Q2 earnings of $0.15 per share on revenue of $9.9 million. Wunderlich downgraded Airgain from Buy to Hold.
- Childrens Place Inc PLCE shares declined 4.1 percent to $79.42. Piper Jaffray downgraded Childrens Place from Overweight to Neutral and lowered the price target from $99 to $88.
- CarMax, Inc KMX shares fell 2.6 percent to $54.33 following Q2 results. While its adjusted earnings came in line, revenue was below Street estimates.
- American Airlines Group Inc AAL fell 2.3 percent to $34.33. Raymond James downgraded American Airlines from Outperform to Market Perform.
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