| Mar 19, 2026 | Yu-Waye Chu | CHIEF MEDICAL OFFICER | -21.28K | $6.42 | -$136.68K | SELL | -10.10% | 189.45K | Mar 17 | View |
| Mar 19, 2026 | Sean A McCarthy | CEO | -118.97K | $6.42 | -$764.14K | SELL | -9.21% | 1.17M | Mar 17 | View |
| Mar 19, 2026 | Marcia Belvin | SVP, CHIEF SCIENTIFIC OFFICER | -31.49K | $6.42 | -$202.27K | SELL | -9.48% | 300.76K | Mar 17 | View |
| Mar 19, 2026 | Christopher Ogden | CHIEF FINANCIAL OFFICER | -19.32K | $6.42 | -$124.11K | SELL | -6.11% | 296.95K | Mar 17 | View |
| Nov 10, 2025 | Sean A McCarthy | CEO | -101.79K | $4.54 | -$461.91K | SELL | -8.61% | 1.08M | Nov 06 | View |
| Jun 17, 2025 | Christopher Ogden | CHIEF FINANCIAL OFFICER | 25.25K | $2.72 | -$33.38K | SELL-OPTIONS | 12.56% | 226.27K | Jun 13 - Jun 16 | View |
| Jun 17, 2025 | Marcia Belvin | SVP, CHIEF SCIENTIFIC OFFICER | 23.62K | $2.69 | -$37.33K | SELL-OPTIONS | 9.50% | 272.25K | Jun 13 - Jun 16 | View |
| Jun 17, 2025 | Sean A McCarthy | CEO | 94.49K | $2.69 | -$149.26K | SELL-OPTIONS | 8.68% | 1.18M | Jun 13 - Jun 16 | View |
| Mar 20, 2025 | Sean A McCarthy | CEO | -37.66K | $0.60 | -$22.56K | SELL | -3.34% | 1.09M | Mar 18 | View |
| Mar 20, 2025 | Christopher Ogden | CHIEF FINANCIAL OFFICER | -8.55K | $0.60 | -$5.12K | SELL | -4.08% | 201.03K | Mar 18 | View |
| Mar 20, 2025 | Yu-Waye Chu | CHIEF MEDICAL OFFICER | -4.03K | $0.60 | -$2.41K | SELL | -2.88% | 135.72K | Mar 18 | View |
| Mar 20, 2025 | Lloyd Rowland | GENERAL COUNSEL | -10.20K | $0.60 | -$6.11K | SELL | -7.80% | 120.59K | Mar 18 | View |
| Mar 20, 2025 | Marcia Belvin | SVP, CHIEF SCIENTIFIC OFFICER | -19.51K | $0.60 | -$11.69K | SELL | -7.28% | 248.64K | Mar 18 | View |
| Aug 22, 2024 | Jeffrey B Landau | CHIEF BUSINESS OFFICER | 7.07K | $1.23 | -$5.14K | SELL-OPTIONS | 6.14% | 122.24K | Aug 20 | View |
| Aug 22, 2024 | Marcia Belvin | SVP, CHIEF SCIENTIFIC OFFICER | 7.07K | $1.23 | -$5.14K | SELL-OPTIONS | 4.19% | 175.65K | Aug 20 | View |
| Aug 22, 2024 | Lloyd Rowland | GENERAL COUNSEL | 7.07K | $1.23 | -$5.14K | SELL-OPTIONS | 5.71% | 130.80K | Aug 20 | View |
| Aug 22, 2024 | Christopher Ogden | CHIEF FINANCIAL OFFICER | 4.89K | $1.23 | -$2.44K | SELL-OPTIONS | 4.74% | 108.08K | Aug 20 | View |
| Aug 22, 2024 | Sean A McCarthy | CEO | 23.60K | $1.23 | -$17.08K | SELL-OPTIONS | 3.24% | 751.01K | Aug 20 | View |
| Mar 21, 2024 | Lloyd Rowland | GENERAL COUNSEL | -5.27K | $2.09 | -$10.99K | SELL | -4.28% | 117.73K | Mar 19 | View |
| Mar 21, 2024 | Sean A McCarthy | CEO | -20.22K | $2.09 | -$42.18K | SELL | -3.17% | 617.64K | Mar 19 | View |
| Mar 21, 2024 | Christopher Ogden | SVP, FINANCE AND ACCOUNTING | -2.97K | $2.09 | -$6.20K | SELL | -3.35% | 85.69K | Mar 19 | View |
| Mar 21, 2024 | Marcia Belvin | SVP, CHIEF SCIENTIFIC OFFICER | -12.79K | $2.09 | -$26.68K | SELL | -7.05% | 168.58K | Mar 19 | View |
| Mar 21, 2024 | Jeffrey B Landau | CHIEF BUSINESS OFFICER | -6.56K | $2.09 | -$13.69K | SELL | -5.48% | 113.24K | Mar 19 | View |
| Dec 22, 2023 | Sean A McCarthy | CEO | -13.55K | $1.38 | -$18.71K | SELL | -2.41% | 547.86K | Dec 20 | View |
| Dec 22, 2023 | Marcia Belvin | SVP, CHIEF SCIENTIFIC OFFICER | -4.08K | $1.38 | -$5.63K | SELL | -2.56% | 155.12K | Dec 20 | View |
| Dec 22, 2023 | Jeffrey B Landau | CHIEF BUSINESS OFFICER | -4.08K | $1.38 | -$5.63K | SELL | -4.34% | 89.80K | Dec 20 | View |
| Dec 22, 2023 | Lloyd Rowland | GENERAL COUNSEL | -4.08K | $1.38 | -$5.63K | SELL | -3.99% | 98.00K | Dec 20 | View |
| Dec 22, 2023 | Christopher Ogden | SVP, FINANCE AND ACCOUNTING | -1.99K | $1.38 | -$2.75K | SELL | -3.93% | 48.66K | Dec 20 | View |
| Sep 22, 2023 | Marcia Belvin | SVP, CHIEF SCIENTIFIC OFFICER | 7.13K | $1.30 | -$5.36K | GRANT | 5.06% | 147.95K | Sep 20 - Sep 22 | View |
| Sep 22, 2023 | Jeffrey B Landau | CHIEF BUSINESS OFFICER | 7.13K | $1.30 | -$5.36K | GRANT | 9.85% | 79.56K | Sep 20 - Sep 22 | View |
| Sep 22, 2023 | Sean A McCarthy | CEO | 25.40K | $1.30 | -$18.99K | GRANT | 5.09% | 523.91K | Sep 20 - Sep 22 | View |
| Sep 22, 2023 | Lloyd Rowland | GENERAL COUNSEL | 9.51K | $1.30 | -$7.14K | GRANT | 13.38% | 80.61K | Sep 20 - Sep 22 | View |
| Mar 31, 2023 | Elaine V Jones | — | 5.00K | $1.55 | $7.75K | BUY | 3521.13% | 5.14K | Mar 29 | View |
| Mar 20, 2023 | Christopher Ogden | SVP, FINANCE AND ACCOUNTING | -516.00 | $1.98 | -$1.02K | SELL | -1.35% | 37.77K | Mar 16 | View |
| Mar 20, 2023 | Carlos Campoy | CHIEF FINANCIAL OFFICER | -1.75K | $1.98 | -$3.46K | SELL | -4.37% | 38.22K | Mar 16 | View |
| Mar 20, 2023 | Sean A McCarthy | CEO | -7.12K | $1.88 | -$13.39K | SELL | -1.46% | 481.98K | Mar 16 | View |
| Mar 20, 2023 | Lloyd Rowland | GENERAL COUNSEL | -2.04K | $1.98 | -$4.03K | SELL | -2.79% | 71.09K | Mar 16 | View |
| Mar 20, 2023 | Jeffrey B Landau | CHIEF FINANCIAL OFFICER | -1.48K | $1.98 | -$2.92K | SELL | -2.00% | 72.43K | Mar 16 | View |
| Mar 20, 2023 | Amy C Peterson | EVP, CHIEF DEVELOPMENT OFFICER | -4.26K | $1.98 | -$8.42K | SELL | -6.79% | 58.43K | Mar 16 | View |
| Jul 21, 2022 | Amy C Peterson | EVP, CHIEF DEVELOPMENT OFFICER | 12.54K | $1.42 | -$10.61K | GRANT | 25.00% | 62.69K | Jul 19 - Jul 20 | View |
| Jul 21, 2022 | Jeffrey B Landau | CHIEF BUSINESS OFFICER | 7.04K | $1.42 | -$5.98K | GRANT | 26.22% | 33.91K | Jul 19 - Jul 20 | View |
| Jul 21, 2022 | Sean A McCarthy | PRESIDENT AND CEO | 25.09K | $1.42 | -$21.21K | GRANT | 6.99% | 384.10K | Jul 19 - Jul 20 | View |
| Jul 21, 2022 | Lloyd Rowland | GENERAL COUNSEL | 9.40K | $1.42 | -$7.97K | GRANT | 27.41% | 43.69K | Jul 19 - Jul 20 | View |
| Jul 21, 2022 | Alison L Hannah | CHIEF MEDICAL OFFICER | 9.40K | $1.42 | -$7.97K | GRANT | 41.77% | 31.90K | Jul 19 - Jul 20 | View |
| Jul 21, 2022 | Carlos Campoy | CHIEF FINANCIAL OFFICER | 11.05K | $1.42 | -$5.62K | GRANT | 38.21% | 39.97K | Jul 19 - Jul 20 | View |
| Jun 21, 2021 | Sean A McCarthy | PRESIDENT AND CEO | -100.00K | $7.04 | -$704.47K | SELL | -49.76% | 100.97K | Jun 16 | View |
| Apr 02, 2021 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $4.31 | -$636.08K | SELL-OPTIONS | 0.00% | 206.89K | Mar 31 | View |
| May 14, 2020 | Sean A McCarthy | — | 0.00 | $8.07 | -$499.18K | OPTION EXERCISE | 0.00% | 84.31K | May 12 | View |
| Mar 05, 2019 | Lloyd Rowland | GENERAL COUNSEL | 9.00K | $10.33 | $92.97K | BUY | 919.31% | 9.98K | Mar 04 | View |
| Dec 14, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $8.22 | -$40.65K | SELL-OPTIONS | 0.00% | 5.93K | Dec 12 | View |
| Nov 05, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $8.22 | -$40.65K | SELL-OPTIONS | 0.00% | 5.93K | Nov 01 | View |
| Nov 05, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $8.29 | -$87.62K | SELL-OPTIONS | 0.00% | 82.06K | Nov 01 - Nov 02 | View |
| Oct 02, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $9.95 | -$51.03K | SELL-OPTIONS | 0.00% | 5.93K | Oct 01 | View |
| Sep 06, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $11.92 | -$62.82K | SELL-OPTIONS | 0.00% | 5.93K | Sep 04 | View |
| Sep 06, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $11.72 | -$264.79K | SELL-OPTIONS | 0.00% | 82.06K | Sep 04 | View |
| Aug 02, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $13.66 | -$74.32K | SELL-OPTIONS | 0.00% | 5.93K | Aug 01 | View |
| Jul 09, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $13.32 | -$105.61K | SELL-OPTIONS | 0.00% | 82.06K | Jul 05 | View |
| Jul 06, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $13.33 | -$47.69K | SELL-OPTIONS | 0.00% | 82.06K | Jul 03 | View |
| Jul 03, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $11.91 | -$63.90K | SELL-OPTIONS | 0.00% | 5.93K | Jul 02 | View |
| Jul 03, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $12.50 | -$285.15K | SELL-OPTIONS | 0.00% | 82.06K | Jul 02 | View |
| Jun 05, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 1.19K | $15.95 | -$52.76K | SELL-OPTIONS | 25.04% | 5.93K | May 31 - Jun 01 | View |
| May 02, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $13.89 | -$75.78K | SELL-OPTIONS | 0.00% | 4.74K | May 01 | View |
| May 02, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $14.06 | -$488.91K | SELL-OPTIONS | 0.00% | 158.88K | May 01 | View |
| Apr 04, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $14.69 | -$80.58K | SELL-OPTIONS | 0.00% | 4.74K | Apr 02 | View |
| Mar 27, 2018 | Frederick W Gluck | DIRECTOR | -5.00K | $31.93 | -$159.64K | SELL | -1.79% | 274.84K | Mar 26 | View |
| Mar 05, 2018 | Frederick W Gluck | DIRECTOR | -16.18K | $30.00 | -$485.47K | SELL | -5.47% | 279.84K | Mar 02 | View |
| Mar 05, 2018 | Rachel Humphrey | CHIEF MEDICAL OFFICER | 0.00 | $18.31 | -$377.91K | SELL-OPTIONS | 0.00% | 30.23K | Mar 02 | View |
| Mar 05, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | 0.00 | $15.60 | -$949.94K | SELL-OPTIONS | 0.00% | 4.74K | Mar 01 - Mar 02 | View |
| Mar 05, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $15.40 | -$549.32K | SELL-OPTIONS | 0.00% | 158.88K | Mar 01 | View |
| Mar 02, 2018 | Rachel Humphrey | CHIEF MEDICAL OFFICER | 0.00 | $18.31 | -$557.51K | SELL-OPTIONS | 0.00% | 30.23K | Feb 28 | View |
| Mar 02, 2018 | Frederick W Gluck | DIRECTOR | -3.82K | $30.00 | -$114.57K | SELL | -1.27% | 296.02K | Feb 28 | View |
| Feb 02, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.55K | $26.69 | -$68.01K | SELL | -34.96% | 4.74K | Feb 01 | View |
| Jan 09, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $13.07 | -$155.82K | SELL-OPTIONS | 0.00% | 163.38K | Jan 05 | View |
| Jan 08, 2018 | Frederick W Gluck | DIRECTOR | -10.00K | $25.01 | -$250.08K | SELL | -3.23% | 299.84K | Jan 05 | View |
| Jan 04, 2018 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $11.09 | -$259.81K | SELL-OPTIONS | 0.00% | 163.38K | Jan 02 | View |
| Jan 03, 2018 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.50K | $21.11 | -$52.77K | SELL | -25.54% | 7.29K | Jan 02 | View |
| Dec 28, 2017 | Frederick W Gluck | DIRECTOR | -5.00K | $22.29 | -$111.43K | SELL | -1.59% | 309.84K | Dec 26 | View |
| Dec 05, 2017 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.34K | $16.36 | -$49.47K | SELL | -19.27% | 9.79K | Nov 30 - Dec 01 | View |
| Dec 05, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 398.00 | $10.99 | -$275.08K | SELL-OPTIONS | 0.24% | 163.38K | Nov 30 - Dec 01 | View |
| Nov 03, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $10.40 | -$271.28K | SELL-OPTIONS | 0.00% | 162.98K | Nov 01 | View |
| Nov 03, 2017 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.50K | $20.00 | -$50.00K | SELL | -17.09% | 12.13K | Nov 01 | View |
| Oct 06, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $12.54 | -$443.30K | SELL-OPTIONS | 0.00% | 162.98K | Oct 04 | View |
| Oct 06, 2017 | Michael Kavanaugh | CSO, HEAD RES.&NON-CLIN. DEV. | 0.00 | $14.41 | -$960.94K | SELL-OPTIONS | 0.00% | 13.92K | Oct 04 | View |
| Oct 06, 2017 | Frederick W Gluck | DIRECTOR | -10.00K | $24.27 | -$242.68K | SELL | -3.08% | 314.84K | Oct 04 | View |
| Oct 04, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $9.76 | -$168.53K | SELL-OPTIONS | 0.00% | 162.98K | Oct 02 | View |
| Oct 04, 2017 | Robert I Tepper | 10% OWNER | -24.78K | $24.34 | -$603.07K | SELL | -0.57% | 4.35M | Oct 04 | View |
| Oct 04, 2017 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.50K | $18.10 | -$45.25K | SELL | -14.60% | 14.63K | Oct 02 | View |
| Sep 27, 2017 | Frederick W Gluck | DIRECTOR | -5.00K | $17.30 | -$86.48K | SELL | -1.52% | 324.84K | Sep 26 | View |
| Sep 21, 2017 | Robert I Tepper | 10% OWNER | -20.00K | $18.00 | -$360.00K | SELL | -0.46% | 4.37M | Sep 19 | View |
| Sep 05, 2017 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.50K | $17.17 | -$42.93K | SELL | -12.74% | 17.13K | Sep 01 | View |
| Sep 05, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $9.13 | -$162.60K | SELL-OPTIONS | 0.00% | 162.98K | Sep 01 | View |
| Sep 01, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $9.22 | -$310.54K | SELL-OPTIONS | 0.00% | 162.98K | Aug 31 | View |
| Aug 11, 2017 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.50K | $15.00 | -$37.50K | SELL | -11.30% | 19.63K | Aug 09 | View |
| Aug 11, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $7.97 | -$67.20K | SELL-OPTIONS | 0.00% | 162.98K | Aug 09 | View |
| Jul 06, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $8.23 | -$69.68K | SELL-OPTIONS | 0.00% | 162.98K | Jul 03 | View |
| Jul 06, 2017 | Debanjan Ray | CHIEF FINANCIAL OFFICER | -2.50K | $15.47 | -$38.67K | SELL | -10.15% | 22.13K | Jul 03 | View |
| Jun 30, 2017 | Robert I Tepper | 10% OWNER | -15.00K | $16.00 | -$240.00K | SELL | -0.29% | 5.22M | Jun 29 | View |
| Jun 27, 2017 | Frederick W Gluck | DIRECTOR | -5.00K | $14.61 | -$73.05K | SELL | -1.49% | 329.84K | Jun 26 | View |
| Jun 27, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 8.96K | $7.97 | $71.45K | SELL-OPTIONS | 5.82% | 162.98K | Jun 26 | View |
| Jun 06, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $7.97 | -$4.22K | SELL-OPTIONS | 0.00% | 162.98K | Jun 05 | View |
| May 02, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $8.32 | -$70.54K | SELL-OPTIONS | 0.00% | 160.72K | May 01 | View |
| Apr 14, 2017 | Kevin Starr | 10% OWNER | -28.36K | $16.36 | -$463.79K | SELL | -0.54% | 5.20M | Apr 12 | View |
| Apr 05, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $9.08 | -$155.62K | SELL-OPTIONS | 0.00% | 160.72K | Apr 03 - Apr 04 | View |
| Mar 27, 2017 | THIRD ROCK VENTURES LPThird Rock Ventures GP LPTRV GP LLCMARK LEVINKEVIN STARRROBERT TEPPER | 10% OWNER | -1.65M | $17.39 | -$28.70M | SELL | -23.98% | 5.23M | Mar 23 - Mar 27 | View |
| Mar 27, 2017 | Neil Exter | DIRECTOR | 0.00 | $0.00 | $0.00 | s | 0.00% | 11.20K | Mar 23 - Mar 27 | View |
| Mar 21, 2017 | Robert C. Goeltz II | CHIEF FINANCIAL OFFICER | 0.00 | $12.14 | -$330.10K | SELL-OPTIONS | 0.00% | 9.79K | Mar 20 | View |
| Mar 21, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $10.27 | -$267.57K | SELL-OPTIONS | 0.00% | 160.72K | Mar 20 | View |
| Mar 03, 2017 | Sean A McCarthy | PRESIDENT AND CEO | 0.00 | $8.07 | -$198.88K | SELL-OPTIONS | 0.00% | 160.72K | Mar 03 | View |
| Dec 01, 2016 | Timothy Shannon | DIRECTOR | -22.09K | $11.18 | -$247.01K | SELL | -0.68% | 3.24M | Nov 29 | View |
| Dec 01, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -422.09K | $11.18 | -$247.01K | SELL | -11.51% | 3.24M | Nov 29 - Nov 30 | View |
| Nov 28, 2016 | Timothy Shannon | DIRECTOR | -38.46K | $11.56 | -$444.40K | SELL | -1.04% | 3.67M | Nov 23 - Nov 28 | View |
| Nov 28, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -38.46K | $11.56 | -$444.40K | SELL | -1.04% | 3.67M | Nov 23 - Nov 28 | View |
| Nov 22, 2016 | Timothy M Shannon | DIRECTOR | -42.55K | $11.71 | -$498.08K | SELL | -1.14% | 3.71M | Nov 22 | View |
| Nov 22, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -42.55K | $11.71 | -$498.08K | SELL | -1.14% | 3.70M | Nov 22 | View |
| Nov 21, 2016 | Timothy M Shannon | DIRECTOR | -45.32K | $11.61 | -$526.09K | SELL | -1.19% | 3.75M | Nov 17 - Nov 21 | View |
| Nov 21, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -45.32K | $11.61 | -$526.09K | SELL | -1.20% | 3.75M | Nov 17 - Nov 21 | View |
| Nov 16, 2016 | Timothy Shannon | DIRECTOR | -51.58K | $11.50 | -$593.43K | SELL | -1.34% | 3.79M | Nov 15 - Nov 16 | View |
| Nov 16, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -51.58K | $11.50 | -$593.43K | SELL | -1.34% | 3.79M | Nov 15 - Nov 16 | View |
| Nov 14, 2016 | Timothy Shannon | DIRECTOR | -86.27K | $11.16 | -$962.91K | SELL | -2.19% | 3.84M | Nov 10 - Nov 14 | View |
| Nov 14, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -86.27K | $11.16 | -$962.91K | SELL | -2.19% | 3.84M | Nov 10 - Nov 14 | View |
| Nov 10, 2016 | Timothy Shannon | DIRECTOR | -13.73K | $11.03 | -$151.50K | SELL | -0.35% | 3.93M | Nov 09 | View |
| Nov 10, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -13.73K | $11.03 | -$151.50K | SELL | -0.35% | 3.93M | Nov 09 | View |
| Jun 10, 2016 | TIMOTHY SHANNON | DIRECTOR | -48.43K | $10.07 | -$487.50K | SELL | -1.13% | 4.24M | Jun 08 - Jun 10 | View |
| Jun 10, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -48.43K | $10.07 | -$487.50K | SELL | -1.13% | 4.24M | Jun 08 - Jun 10 | View |
| Jun 08, 2016 | TIMOTHY SHANNON | DIRECTOR | -111.50K | $10.01 | -$1.12M | SELL | -2.53% | 4.29M | Jun 06 - Jun 07 | View |
| Jun 08, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -111.50K | $10.01 | -$1.12M | SELL | -2.53% | 4.29M | Jun 06 - Jun 07 | View |
| Jun 06, 2016 | TIMOTHY SHANNON | DIRECTOR | -59.62K | $10.80 | -$644.05K | SELL | -1.34% | 4.40M | Jun 02 - Jun 03 | View |
| Jun 06, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -59.62K | $10.80 | -$644.05K | SELL | -1.34% | 4.40M | Jun 02 - Jun 03 | View |
| Jun 02, 2016 | TIMOTHY SHANNON | DIRECTOR | -22.46K | $10.75 | -$241.48K | SELL | -0.50% | 4.46M | Jun 01 | View |
| Jun 02, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -22.46K | $10.75 | -$241.48K | SELL | -0.50% | 4.46M | Jun 01 | View |
| Jun 01, 2016 | TIMOTHY SHANNON | DIRECTOR | -25.08K | $10.60 | -$265.87K | SELL | -0.56% | 4.49M | May 27 | View |
| Jun 01, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -25.08K | $10.60 | -$265.87K | SELL | -0.56% | 4.49M | May 27 | View |
| May 27, 2016 | TIMOTHY SHANNON | DIRECTOR | -51.34K | $10.34 | -$530.81K | SELL | -1.13% | 4.51M | May 25 - May 26 | View |
| May 27, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -51.34K | $10.34 | -$530.81K | SELL | -1.13% | 4.51M | May 25 - May 26 | View |
| May 25, 2016 | TIMOTHY SHANNON | — | -13.25K | $10.09 | -$133.74K | SELL | -0.29% | 4.56M | May 23 - May 24 | View |
| May 25, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -13.25K | $10.09 | -$133.74K | SELL | -0.29% | 4.56M | May 23 - May 24 | View |
| May 23, 2016 | TIMOTHY SHANNON | — | -8.69K | $10.10 | -$87.78K | SELL | -0.19% | 4.58M | May 19 - May 20 | View |
| May 23, 2016 | Canaan IX LPCanaan Partners IX LLC | DIRECTOR | -8.69K | $10.10 | -$87.78K | SELL | -0.19% | 4.58M | May 19 - May 20 | View |
| Oct 16, 2015 | Cynthia J Ladd | SENIOR VP AND GENERAL COUNSEL | 3.00K | $12.00 | $36.00K | BUY | ∞ | 3.00K | Oct 14 | View |
| Oct 16, 2015 | Michael William Kavanaugh | CSO, HEAD RES.&NON-CLIN. DEV. | 5.00K | $12.00 | $60.00K | BUY | ∞ | 5.00K | Oct 14 | View |
| Oct 16, 2015 | FREDERICK GLUCK | DIRECTOR | 15.00K | $12.00 | $180.00K | BUY | ∞ | 8.20K | Oct 14 | View |
| Oct 14, 2015 | James FlynnDeerfield Mgmt LPCO MANAGEMENT DEERFIELDDeerfield Special Situations Fund LPDeerfield Mgmt III LPDeerfield Private Design Fund III LP | 10% OWNER | 946.02K | $12.00 | $7.50M | BUY | ∞ | 275.00K | Oct 14 | View |
