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Amplia Therapeutics (OTC:INNMF) Stock, Option Chain

Amplia Therapeutics Ltd is an Australian pharmaceutical company advancing a pipeline of Focal Adhesion Kinase (FAK) inhibitors for cancer and fibrosis. Its molecule, AMP945 is a pure-play inhibitor, while the second molecule, AMP886, is a multi-action molecule that hits two other important cancer pathways - VEGFR3 and FLT3.

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AMPLIA THERAPEUTICS LTD by Amplia Therapeutics Ltd.

Amplia Therapeutics Ltd

Chinese startup DeepSeek has upended the artificial intelligence industry&#8217;s assumptions about costs and computing power, just as OpenAI announced its latest model can cost up to $3,000 per query.
DeepSeek&#8217;s R1 model, which rivals top U.S. systems in performance, reportedly cost just $5.6 million to develop. The breakthrough sent shocks through global markets Monday, erasing nearly $1 trillion in U.S. and European tech stock value, including a record $589 billion drop in Nvidia&#8217;s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVDA#NASDAQ">NVDA</a>) market capitalization.
&#8220;It&#8217;s a paradigm shift,&#8221; Ali Ghodsi, CEO of Databricks Inc., said to Bloomberg. &#8220;These models that can reason are so much cheaper to produce that you will see it be democratized. You&#8217;ll see innovations from unexpected corners of the world.&#8221;
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Meanwhile, OpenAI&#8217;s new o3 model, announced just before Christmas, signals a contrary trend—achieving breakthrough performance but at staggering costs. The model requires up to $3,000 to solve a single query that humans complete in seconds, using 172 times more computing power than previous approaches.
&#8220;One very important thing to understand about the future: the economics of AI are about to change completely,&#8221; François Chollet, an AI researcher, said on X when o3 went public.
The model&#8217;s success came from its &#8220;test-time compute&#8221; approach, allowing it to think harder about each question. While this produced superior results, including a 91.5% score on Chollet&#8217;s challenging ARC test, it shattered previous cost assumptions about AI services.
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OpenAI, valued at $157 billion, may charge up to $2,000 monthly for full access to o3, according to The Economist, which cited New Street Research analyst Pierre Ferragu. Even the company&#8217;s current &#8220;pro&#8221; version of o1 loses money on its $200 monthly subscription tier due to higher-than-expected usage.
The cost structure challenges the traditional tech industry model of providing services at near-zero marginal cost. It also strengthens the position of suppliers like Nvidia and cloud providers like Amazon (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMZN#NASDAQ">AMZN</a>), Microsoft (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MSFT#NASDAQ">MSFT</a>), and Alphabet (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOG#NASDAQ">GOOG</a>, GOOGL)), which control the essential computing infrastructure. DeepSeek&#8217;s <a href="https://www.benzinga.com/markets/asia/25/01/43243584/deepseek-r1-vs-openai-what-consumers-need-to-know-about-ais-latest-challenger">success suggests an alternative path</a>. Founded by Liang Wenfeng in 2023, the company achieved its results through efficiency innovations and reinforcement learning techniques, despite limited access to advanced U.S. chips.
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&#8220;More investment does not necessarily lead to more innovation,&#8221; Liang told Chinese media outlet 36kr. &#8220;Otherwise, large companies would take over all innovation.&#8221;
The development is catching Silicon Valley&#8217;s attention. OpenAI CEO Sam Altman noted the shift, calling DeepSeek&#8217;s R1 &#8220;an impressive model&#8221; and &#8220;invigorating.&#8221; Meta established an internal team to analyze DeepSeek&#8217;s methods, according to Bloomberg, which cited people familiar with the matter.
Instead of a winner-take-all market, experts predict an oligopoly where multiple firms compete based on specialized applications. Companies like Anthropic, valued at $60 billion, and xAI at $45 billion, suggest investors see room for multiple players despite the high costs.
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'The Economics Of AI Are About To Change Completely': Why OpenAI's o3 Could Reshape The Industry — Costing Up To $3000 Per Query

A recent analysis by The Commonwealth Fund has revealed what many Americans may already suspect: the United States health care system ranks last among wealthy nations. Despite spending more on health care than any other country, the US continues to underperform in critical areas like accessibility, efficiency, equity, and health outcomes.
A Troubling Report Card
In the "Mirror, Mirror 2024: A Portrait of the Failing U.S. Health System" <a href="https://www.commonwealthfund.org/publications/fund-reports/2024/sep/mirror-mirror-2024">report</a>, researchers compared health care systems across 10 high-income countries—Australia, Canada, France, Germany, the Netherlands, New Zealand, Sweden, Switzerland, the United Kingdom, and the United States. The US came in last place overall, ranking 10th in accessibility and health outcomes, and poorly in administrative efficiency and equity.
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According to a September article in AJMC, Joseph Betancourt, MD, president of The Commonwealth Fund, summed it up saying: "The US is failing one of its principal obligations as a nation: to protect the health and welfare of its people… Continually spending the most and getting the least for our health care dollars is not sustainable."
What's Holding the US Back?
One of the <a href="https://www.benzinga.com/personal-finance/25/01/43218719/medicares-at-home-care-and-telehealth-restrictions-in-2025-could-limit-access-to-affordable-healthcare-heres-what-you-need-to-know">biggest issues is access to care</a>. With 26 million uninsured Americans and sky-high out-of-pocket costs, health care remains out of reach for many. In contrast, countries like the Netherlands and Germany offer universal coverage and affordable care, making access far more equitable.
The <a href="https://www.benzinga.com/personal-finance/24/12/42742855/mark-cuban-says-this-is-single-payer-how-his-healthcare-model-could-transform-the-u-s-healthcare-system">shortcomings of the US health care system</a> are further evident in its unparalleled spending. According to the Peter G. Peterson Foundation, in 2022, the United States spent an estimated $12,742 per person on health care—the highest per capita spending among wealthy nations. For comparison, Switzerland, the second-highest spender, allocated $9,044 per person, while the average for other Organization for Economic Development Cooperative and Development countries, excluding the US, was just $6,850.&nbsp;
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Administrative inefficiency is another key weakness. The US ranked ninth in the category due to its complex insurance system, which forces patients and providers to navigate endless denials, appeals, and paperwork.&nbsp;
In terms of equity, the US fared poorly as well, with widespread disparities in care based on race, ethnicity, and income. Issues like racial discrimination and uneven access to resources disproportionately impact vulnerable communities, worsening health outcomes for millions.
Finally, the US performed the worst in health outcomes. The country has the highest rate of preventable deaths, along with a lower-than-average life expectancy, driven by factors like the opioid crisis, gun violence, and chronic diseases.
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What Can Be Done?
The report emphasizes that the US health care system could learn a lot from other nations. Here's what researchers suggest:
<ul>
<li>Reduce financial barriers: Expand insurance coverage and ensure it protects against high out-of-pocket costs.</li>
<li>Simplify the system: Streamline administrative processes to reduce inefficiencies for both patients and providers.</li>
<li>Strengthen primary care: Invest in training and compensation for primary care providers to improve access and outcomes.</li>
<li>Address inequities: Combat racial and socioeconomic disparities by expanding social safety nets and addressing social determinants of health, like housing and food security.</li>
<li>Tackle market consolidation: Regulate health care mergers to reduce costs and improve access.</li>
</ul>
As Betancourt put it, "This report underscores the many lessons we could learn from others on how to strengthen our health care delivery and outcomes."
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The Bottom Line
The US health care system's high spending has not translated into better health outcomes or broader access. It's clear that reform is overdue, with opportunities to build a system that is more equitable, efficient, and effective for all Americans. By learning from other nations, the US could finally turn its spending into meaningful improvements for its citizens.
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US Health Care Ranks Last Among Wealthy Nations — Study Reveals Despite Highest Spending, People Have Lower-Than-Average Life Expectancies

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