Short interest in Spero Therapeutics Inc (NASDAQ:SPRO) increased during the last reporting period, rising from 387.07K to 625.19K. This put 1.41% of the company's publicly available shares short.

Short interest for Spero Therapeutics gives investors a sense of the degree to which investors are betting on the decline of Spero Therapeutics's stock. Short interest data is updated every two weeks.

Based on the recent average volume of 417.64K shares traded per day, it would take 1.5 day(s) for holders of this short interest to close out their positions without sending the stock sharply higher.