Short interest in Spero Therapeutics Inc (NASDAQ:SPRO) decreased during the last reporting period, falling from 493.83K to 451.22K. This put 1.01% of the company's publicly available shares short.

Short interest for Spero Therapeutics gives investors a sense of the degree to which investors are betting on the decline of Spero Therapeutics's stock. Short interest data is updated every two weeks.

Based on the recent average volume of 160.64K shares traded per day, it would take 2.81 day(s) for holders of this short interest to close out their positions without sending the stock sharply higher.