Option chain shows key data for Zalatoris Acquisition's stock options at various strike prices and expiration dates. Traders use this information to analyze potential trades and assess market sentiment for Zalatoris Acquisition.

Zalatoris Acquisition (OTC:TCOAW) Stock, Option Chain

Zalatoris Acquisition Corp, formerly Trajectory Alpha Acquisition Corp is a blank check company.

Zalatoris Acquisition Corp Warrants (01/01/9999)

Zalatoris Acquisition Corp

A recent report revealed the environmental violations at Tesla Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TSLA#NASDAQ">TSLA</a>)&#8217;s Austin and Freemont plants amid Elon Musk being announced as the co-head of a new Department of Government Efficiency, dubbed &#8220;DOGE,&#8221; aimed at reducing regulations.
What Happened:&nbsp;According to the Journal, Tesla&#8217;s Austin facility has been releasing toxic pollutants due to malfunctioning equipment, such as a giant casting furnace door that failed to close properly. This issue led to increased emissions and hazardous working conditions, The Wall Street Journal <a href="https://www.wsj.com/business/autos/elon-musk-tesla-environment-1263cd60">reported</a>&nbsp;on Monday.
Emails obtained by the Journal from Texas regulators and interviews with former employees reveal that Tesla was aware of these problems but opted for temporary solutions to maintain production speed. Employees reportedly feared job loss if they highlighted environmental concerns.
The Journal also uncovered that Tesla&#8217;s Fremont, Calif., plant has received numerous air pollution violation warnings&nbsp;over the past five years, second only to a Chevron refinery in California.
See Also:&nbsp;<a href="https://www.benzinga.com/general/social-media/24/11/42155884/economist-slams-doges-simplistic-approach-to-government-spending-questions-super-bowl-ad-criticism?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">Economist Slams DOGE: Tells Elon Musk-Led Initiative To &#8216;Do Your Legal Job Well&#8217; Amid Super Bowl Ad Spend</a>
As Musk assumes his new role, his stance on deregulation raises questions about the future of environmental regulations affecting his companies. 
Tesla and Musk have not responded to <a href="https://pro.benzinga.com">Benzinga</a>&#8216;s requests for comment on these issues.
Why It Matters: The&nbsp;DOGE department, <a href="https://www.benzinga.com/news/24/11/41998717/elon-musk-and-vivek-ramaswamy-are-looking-for-high-iq-small-government-revolutionaries-who-are-willing-to-put-in-80-hours-at-doge">co-led by Musk and&nbsp;Vivek Ramaswamy,</a> aims to reduce federal inefficiencies under President-elect&nbsp;Donald Trump. This initiative seeks high-IQ individuals to work extensively to streamline government operations and reduce bureaucracy.
A month before the announcement, Musk described the <a href="https://www.benzinga.com/markets/cryptocurrency/24/10/41220500/elon-musk-says-potential-doge-department-under-a-trump-administration-will-be-a-garbage-co">potential&nbsp;DOGE department</a>&nbsp;as a &#8220;garbage collection of rules that don&#8217;t make sense.&#8221; His approach to efficiency has been evident in his companies, though it has sometimes led to conflicts with unions.
Read Next:&nbsp;
<ul>
<li><a href="https://www.benzinga.com/24/11/42153039/bizarro-world-people-are-really-confused-by-elon-musk-praising-argentinas-javier-milei-slashing-import-taxes?itm_source=parsely-api" target="_blank" rel="noreferrer noopener">&#8216;Bizarro World&#8217; – People Are Really Confused By Elon Musk Praising Argentina&#8217;s Javier Milei Slashing Import Taxes</a></li>
</ul>
Disclaimer: This content was partially produced with the help of&nbsp;<a href="https://www.benzinga.com/author/benzinga-neuro" target="_blank" rel="noreferrer noopener">Benzinga Neuro</a>&nbsp;and was reviewed and published by Benzinga editors.
Image via Shutterstock

Government

News

Regulations

Tech

General

TSLA

Tesla Faces Environmental Violations As Elon Musk's 'DOGE' Prepares For 'Garbage Collection Of Rules That Don't Make Sense:' Report

Wells Fargo analyst Sam Reid initiates coverage on CSW Industrials (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CSWI#NASDAQ">CSWI</a>) with a Equal-Weight rating and announces Price Target of $425.

Price Target

Initiation

Analyst Ratings

CSWI

Wells Fargo Initiates Coverage On CSW Industrials with Equal-Weight Rating, Announces Price Target of $425

Microsoft Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MSFT#NASDAQ">MSFT</a>) CEO Satya Nadella acknowledged the need for a fundamental cultural shift in the company&#8217;s approach to cybersecurity, following a series of high-profile security incidents that prompted him to take a <a href="https://www.benzinga.com/markets/equities/24/10/41540407/satya-nadellas-salary-rose-63-to-79-1m-but-heres-why-the-microsoft-ceo-is-taking-a-5m-pay-cut">voluntary $5 million reduction in his cash incentive</a>.
What Happened: &#8220;That&#8217;s what will be culture change,&#8221; Nadella told Wired in a recent <a href="https://www.wired.com/story/at-age-50-microsoft-is-an-ai-giant-an-open-source-lover-and-bad-as-it-ever-was/">interview</a>, emphasizing that the transformation wouldn&#8217;t involve internal blame. &#8220;This is not about a witch hunt internally at Microsoft.&#8221;
The call for change comes after several significant security challenges in 2023-2024. The U.S. Department of Homeland Security criticized Microsoft&#8217;s security systems as inadequate in March, particularly noting vulnerabilities to <a href="https://www.benzinga.com/news/23/07/33441264/ron-wyden-accuses-microsoft-of-negligence-in-recent-cybersecurity-breach">China-based hacking group Storm-0588</a>. 
The company also <a href="https://www.benzinga.com/news/24/04/38214476/russian-government-linked-hackers-stole-federal-email-correspondence-with-microsoft-cisa">faced a system compromise</a> by the Russian group Midnight Blizzard, affecting corporate email accounts, and dealt with a <a href="https://www.benzinga.com/news/24/07/39870313/microsoft-crowdstrike-issue-caused-largest-it-outage-in-history-showing-how-much-we-depend-on-a-hand">global IT outage stemming</a> from a CrowdStrike update issue.
Nadella&#8217;s promise, and Microsoft&#8217;s security troubles that precede them, are reminiscent of what happened more than 20 years ago &#8211; back in 2002, after a series of security lapses, Bill Gates <a href="https://www.microsoft.com/en-us/security/blog/2022/01/21/celebrating-20-years-of-trustworthy-computing/">sent</a> a famous memo to all Microsoft employees to launch an initiative called &#8220;Trustworthy Computing.&#8221;
See Also: <a href="https://www.benzinga.com/24/11/42156013/bluesky-adds-millions-of-users-as-elon-musks-social-media-platform-faces-exodus-post-trump-win-here-are-a-few-starter-packs-to-help-you-get-going-on-latest-x-rival">Bluesky Adds Millions Of Users As Elon Musk&#8217;s X Faces Exodus Post Trump Victory: Here Are A Few Starter Packs To Help You Level Up On The Platform</a>
Why It Matters: Brad Smith, Microsoft&#8217;s vice chair and president, formally accepted responsibility for these <a href="https://www.benzinga.com/government/24/06/39312639/microsoft-under-fire-president-brad-smith-to-testify-on-security-lapses-after-major-cyberattacks">security flaws in a June</a> statement to the Department of Homeland Security. The acknowledgment came as Microsoft continued to expand its artificial intelligence initiatives, with Nadella noting that AI development was &#8220;doubling every six months or so.&#8221;
Despite these challenges, Microsoft&#8217;s market value has exceeded $3 trillion, and Nadella&#8217;s total compensation rose 63% to $79.1 million in fiscal 2024, primarily due to stock awards. However, <a href="https://www.benzinga.com/markets/equities/24/10/41540407/satya-nadellas-salary-rose-63-to-79-1m-but-heres-why-the-microsoft-ceo-is-taking-a-5m-pay-cut">demonstrating personal accountability</a>, he requested a reduction in his cash incentive to $5.2 million from an eligible $10.7 million following the cybersecurity incidents.
The security concerns emerge as Microsoft maintains its leadership in generative AI, with over 85% of Fortune 500 companies using its AI tools. JPMorgan analyst Mark Murphy emphasized the company&#8217;s unique position in AI innovation, noting its success in infusing AI across both <a href="https://www.benzinga.com/24/11/42088290/microsoft-defies-the-ai-plateau-pushing-boundaries-with-new-scaling-laws">application and infrastructure stacks</a>.
Nadella highlighted that &#8220;perverse incentives&#8221; often lead companies to prioritize product development over securing existing products, suggesting a need to rebalance these priorities as part of the cultural transformation.
Read Next: 
<ul>
<li><a href="https://www.benzinga.com/news/global/24/11/42156160/palantir-price-target-raised-to-75-by-dan-ives-amid-288-ytd-surge-analyst-calls-2025-a-primetime-year-for-ai">Palantir Price Target Raised To $75 By Dan Ives Amid 288% YTD Surge: Analyst Calls 2025 A &#8216;Primetime&#8217; Year For AI</a></li>
</ul>
Microsoft CEO Satya Nadella. Photo by WEF on Flickr
Disclaimer: This content was partially produced with the help of&nbsp;<a href="https://www.benzinga.com/author/benzinga-neuro" target="_blank" rel="noreferrer noopener">Benzinga Neuro</a>&nbsp;and was reviewed and published by Benzinga editors.

Markets

MSFT

Satya Nadella Promises 'Culture Change' After Security Lapses Return To Haunt Microsoft 20 Years After Bill Gates Launched A Similar Initiative

Earnings

HTLM

HomesToLife Reported H1 Net Revenue Of $1.99M, Down By 21% YoY, EPS Loss Of $(0.03)

HC Wainwright &amp; Co. analyst Mitchell Kapoor reiterates Oruka Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ORKA#NASDAQ">ORKA</a>) with a Buy and maintains $45 price target.

Reiteration

ORKA

HC Wainwright & Co. Reiterates Buy on Oruka Therapeutics, Maintains $45 Price Target

HC Wainwright &amp; Co. analyst Mitchell Kapoor reiterates Halozyme Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HALO#NASDAQ">HALO</a>) with a Buy and maintains $68 price target.

HALO

HC Wainwright & Co. Reiterates Buy on Halozyme Therapeutics, Maintains $68 Price Target

Wells Fargo analyst Stephen Baxter downgrades Tenet Healthcare (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/THC#NYSE">THC</a>) from Overweight to Equal-Weight and lowers the price target from $205 to $150.

Downgrades

Wells Fargo Downgrades Tenet Healthcare to Equal-Weight, Lowers Price Target to $150

Needham analyst Gil Blum reiterates Cartesian Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RNAC#NASDAQ">RNAC</a>) with a Buy and maintains $41 price target.

RNAC

Needham Reiterates Buy on Cartesian Therapeutics, Maintains $41 Price Target

Catalyst Bancorp, Inc. (Nasdaq: "CLST") (the "Company"), the parent company for Catalyst Bank (the "Bank") (<a href="http://www.catalystbank.com/">www.catalystbank.com</a>), announced today that the Board of Directors approved the Company's fifth share repurchase plan.&nbsp;
"It has been over three years since we embarked on our public company journey. We've set ambitious goals to transform ourselves into a consistently strong performing community bank. High among those goals is focusing our mission on serving as catalysts to help local businesses grow – because when they do, they create jobs in our communities. We rebranded as Catalyst Bank to reinforce our commitment," said Joe Zanco, President and Chief Executive Officer of the Company and Bank.
"We have expanded our branch network into the business center of our region, adding locations in Carencro and Lafayette, Louisiana. Although we increased our branch count by two, or 50%, we have held our employee count steady by focusing on enhancing efficiency throughout the Company.&nbsp;
"We have upgraded our systems and now offer some of the very best in banking technology. The systems upgrade reduces non-interest expense over $200,000 annually and also facilitates additional efficiency gains.&nbsp;
"Our collective efforts have resulted in meaningful customer growth, especially in 2024.&nbsp; In fact, loan growth through the third quarter was a record $21 million.&nbsp; As a result of organic customer growth and greater efficiency, our core profitability continues to improve.&nbsp;
"Not everything has gone according to plan since our IPO. At the outset of our journey, we believed there might be opportunities to acquire one or more banks during the first three years following our IPO, which would have allowed us to expand our footprint and enhance profitability more rapidly. Unfortunately, the right opportunities have not presented themselves to date.&nbsp; However, we still have the capital and management depth and expertise to take advantage of desirable opportunities should they present themselves in the near future.&nbsp;
"Today, we announced our fifth share repurchase plan (the "November 2024 Repurchase Plan").&nbsp; Under the November 2024 Repurchase Plan, the Company may purchase up to 215,000 shares, or approximately 5%, of the Company's outstanding common stock. Since the announcement of our first share repurchase plan in January 2023 and through November 22, 2024, the Company has repurchased a total of 972,916 shares of its common stock, or approximately 18% of the common shares originally issued, at an average cost per share of $11.93.
"As we enter the new year, know that we are focused on serving our customers tremendously well, deepening the skills of our employees and enhancing our profitability and shareholder value.&nbsp; What we've achieved since our IPO is the result of the efforts of our dynamic team.&nbsp; Our commitment to growing and further improving our company is stronger than ever."

Buybacks

CLST

Catalyst Bancorp Announces Fifth Stock Buyback Plan, Targeting 215,000 Shares

Wells Fargo analyst Stephen Baxter downgrades HCA Healthcare (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/HCA#NYSE">HCA</a>) from Equal-Weight to Underweight and lowers the price target from $400 to $320.

Wells Fargo Downgrades HCA Healthcare to Underweight, Lowers Price Target to $320

Biotech

Health Care

Financing

Offerings

REPL

Replimune Has Proposed Public Offering Of $125M Of Its Common Stock And Pre-funded Warrants To Purchase Shares, The Underwriter Has A 30-day Option To Purchase Up To An Additional $18.75 Million Of Securities

Smartkem (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SMTK#NASDAQ">SMTK</a>), positioned to power the next generation of displays using its disruptive organic thin-film transistors (OTFTs), has partnered with AUO, the largest display manufacturer in Taiwan, to jointly develop the world's first advanced rollable, transparent microLED display using Smartkem's technology.
"We believe that collaborating with global display industry leader AUO to develop a novel microLED display puts Smartkem's technology on the frontier of microLED display commercialization. Our unique transistor technology is expected to enable display manufacturers to efficiently produce microLED displays, making mass production commercially viable. Smartkem's technology has the potential to take today's microLED TVs from high end market prices of $100,000 down to mass market prices," stated Ian Jenks, Smartkem Chairman and CEO.
"Because our transistors are processed at such a low temperature compared to other technologies, we are able to pour them directly on top of the microLEDs, completely eliminating the problematic mass transfer and laser welding processes required with other technologies. The key feature that enables the development of this microLED display is our unique low temperature process that allows the use of low-cost, flexible plastic rather than glass. We believe that, if successful, this collaboration will be a significant milestone for Smartkem in its road to commercialization, and for microLED display product development using our technology."
Dr. Wei-Lung Liau, Chief Technology Officer of AUO, commented, "AUO has dedicated years to developing the ultimate MicroLED display technology, forging alliances with ecosystem partners to enable mass production. In this collaboration, AUO has developed groundbreaking technologies that boost the high transparency and free-form in applications of MicroLED. With proprietary materials from Smartkem and the OTFT production process from ITRI, we are collaboratively developing the world's first rollable MicroLED display for potential commercialization with cost advantage. We believe this will create new opportunities for the display industry and continue to expand value chain partner cooperation and influence."
Leading display analyst and DSCC (Display Supply Chain Consultants) CEO, Ross Young, commented, "This is an exciting project that, if successful, will demonstrate the cost effectiveness of Smartkem's technology in the most demanding of MicroLED applications, and could generate substantial market interest."
Smartkem's Disruption to the MicroLED Display Market Smartkem believes it is poised to transform the display industry with a new class of microLED displays that are low-cost, thin, transparent, flexible and lightweight. This is made possible by Smartkem's OTFTs that are processed at an industry comparatively low temperature, enabling them to be processed directly on top of microLEDs in the manufacturing of microLED displays, eliminating the need for mass transfer and laser welding processes required by existing technology. This introduces an entirely new "Chip-First" display architecture to the display market that is not currently possible using other transistor technologies. Additionally, Smartkem's low temperature feature enables processing of Smartkem's OTFTs on a plastic substrate, rather than glass, that is low-cost, thin, transparent, flexible and lightweight.
The project between Smartkem and AUO will commence on January 1, 2025. The collaboration has been awarded a grant from the 2024 Taiwan-UK Research &amp; Development Collaboration, supported by The Taiwanese Ministry of Economic Affairs and Innovate UK, part of UK Research and Innovation (UKRI).
About the 2024 UK-Taiwan Collaborative R&amp;D Initiative The 2024 UK-Taiwan Collaborative R&amp;D Initiative has invested more than £10 million this year to promote bilateral industrial technology research and development cooperation. The nine award-winning projects will promote the joint development of advanced technologies in fields such as electrical information communication, biomedicine, and electromechanical by Taiwan-UK enterprises.

SMTK

Smartkem Partners With AUO To Develop Rollable, Transparent MicroLED Displays

Wells Fargo analyst Stephen Baxter downgrades Community Health Sys (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CYH#NYSE">CYH</a>) from Equal-Weight to Underweight and lowers the price target from $5 to $2.5.

Wells Fargo Downgrades Community Health Sys to Underweight, Lowers Price Target to $2.5

The effective date of the reverse stock split has not yet been determined and will be announced by the Company at least two business days prior to its implementation.

Stock Split

RNAZ

TransCode Therapeutics Has Approved A 1-for-33 Reverse Stock Split

Semler Scientific, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SMLR#NASDAQ">SMLR</a>), a pioneer in developing and marketing technology products and services to healthcare providers to combat chronic diseases, today announced updates regarding its bitcoin (BTC) activity and holdings, capital markets activity, and BTC yield, a key performance indicator.
&nbsp;
BTC Update
Between November 18, 2024 and November 22, 2024, Semler Scientific acquired 297 bitcoins for $29.1 million in cash, at an average price of $97,995 per bitcoin, inclusive of fees and expenses. As of November 22, 2024, Semler Scientific held 1,570 bitcoins, which were acquired for an aggregate $117.8 million at an average purchase price of $75,039 per bitcoin, inclusive of fees and expenses.
ATM Update
As previously disclosed in Semler Scientific's registration statement on Form S-3 that became effective on August 13, 2024 (the S-3 Shelf), Semler Scientific entered into a Controlled Equity OfferingSM&nbsp;Sales Agreement with Cantor Fitzgerald &amp; Co. (Cantor), pursuant to which Semler Scientific may offer and sell from time to time its common stock in an at-the-market (ATM) offering.
Today, Semler Scientific filed a prospectus supplement to its S-3 Shelf to offer an additional $50.0 million of shares under its existing ATM offering with Cantor, increasing the total amount offered under the ATM to $100.0 million.&nbsp; As of November 22, 2024, Semler Scientific has generated approximately $50.0 million of gross proceeds under the ATM offering.
BTC Yield as a Key Performance Indicator (KPI)
From October 1, 2024 to November 22, 2024, Semler Scientific's BTC Yield was 37.1%. From July 1, 2024 (the quarter after Semler Scientific adopted its bitcoin treasury strategy) to November 22, 2024, Semler Scientific's BTC Yield was 58.4%.
"We are thrilled to report a 58.4% BTC Yield and the outstanding progress we are making to accumulate bitcoin on our balance sheet in a highly accretive way for our stakeholders," said Eric Semler, chairman of Semler Scientific.
Semler Scientific uses BTC Yield as a KPI to help assess the performance of its strategy of acquiring bitcoin in a manner Semler Scientific believes is accretive to stockholders. Semler Scientific believes this KPI can be used to supplement an investor's understanding of Semler Scientific's decision to fund the purchase of bitcoin by issuing additional shares of its common stock.
BTC Yield and Basic and Assumed Diluted Shares Outstanding
<figure class="table"> 
<table>
<tbody>
<tr>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">6/30/2024&nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">9/30/2024&nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">11/22/2024&nbsp;</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Total&nbsp;Bitcoin&nbsp;Holdings</td>
<td colspan="1" rowspan="1">877</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">1,018</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">1,570</td>
</tr>
<tr>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Basic&nbsp;Shares Outstanding&nbsp;('000)</td>
<td colspan="1" rowspan="1">6,987</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">7,120</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">8,289</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Options&nbsp;Outstanding</td>
<td colspan="1" rowspan="1">1,098</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">1,013</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">855</td>
</tr>
<tr>
<td colspan="1" rowspan="1">Assumed&nbsp;Diluted&nbsp;Shares&nbsp;Outstanding&nbsp;(1)</td>
<td colspan="1" rowspan="1">8,086</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">8,133</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">9,143</td>
</tr>
<tr>
<td colspan="1" rowspan="1">BTC&nbsp;Yield&nbsp;%&nbsp;(10/1/24 to 11/22/24)</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">37.1&nbsp;%</td>
</tr>
<tr>
<td colspan="1" rowspan="1">BTC&nbsp;Yield&nbsp;%&nbsp;(7/1/2024 to 11/22/2024)</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1"> &nbsp;</td>
<td colspan="1" rowspan="1">58.4&nbsp;%</td>
</tr>
</tbody>
</table>
</figure>

SMLR

Semler Scientific Increases Bitcoin Holdings to 1,570 BTC With 58.4% Yield, Announces $50M ATM Launch, Adds 297 BTC to Portfolio

Guidance

CRGO

Freightos Expects Q4 Revenue Of $6.4M - $6.5M (Est $6.587M)

<ul>
<li>50% of patients who received repeated doses (n=10) remained alive and in remission beyond the expected median overall survival (OS) from standard-of-care Stupp regimen while none of the patients who received a single dose (n=3) achieved this outcome.</li>
<li>Biopsy results confirmed the presence and persistence of gamma-delta T cells along with CD3+ and CD8+ T cells within the brain tumor microenvironment in two patients following treatment with INB-200.</li>
<li>Patients in the multi-dose cohorts demonstrated a trend toward improved peripheral T cell recovery, suggesting potential immune system benefits.</li>
<li>The majority of patients exceeded their expected progression free survival (PFS) based on age and tumor status; five patients remain alive and three patients have returned to their occupations, with one patient remaining progression free at 40.5 months post treatment.</li>
</ul>

INAB

IN8Bio Presented Results From The Fully Enrolled Phase 1 Trial Of INB-200 At The Annual Meeting Society For Neuro-oncology

2024 Guidance
The company expects the 13-week fourth quarter 2024 net sales to range between a decline of 6.5% to a decline of 4.5%, compared to $2,912 million for the 14-week fourth quarter 2023. We expect fourth quarter net sales will incur a headwind of approximately 500 basis points due to the shifted fiscal calendar, resulting from and including the extra week in 2023. Fourth quarter earnings per diluted share is expected to be between $1.94 and $2.07, compared to $2.55 in the fourth quarter 2023, and adjusted earnings per diluted share of $2.06 in the fourth quarter 2023.

BBWI

Bath & Body Works Expects Q4 Net Sales To Decline Of 6.5% To Decline Of 4.5%; Sees EPS Of $1.94-$2.07 Vs. $1.97 Est.

Freightos Says Full-year Revenue Guidance Now At Higher End Of Previous Range; Revises Forecast From $23.4M - $23.7M To $23.6M - $ 23.7M (Est $23.549M)

Abbott (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ABT#NYSE">ABT</a>) today announced the first patient procedures with its investigational transcatheter aortic valve implantation (TAVI) balloon-expandable system for treating&nbsp;symptomatic severe aortic stenosis. This investigational Abbott TAVI system is the first step toward Abbott's software-guided balloon-expandable TAVI system&nbsp;and is designed to build a foundation for artificial intelligence (AI) guided procedures. Once the investigational balloon-expandable system completes clinical development and is approved by regulatory authorities, Abbott's structural heart portfolio will offer physicians another TAVI management option to meet the patient's&nbsp;needs along with the company's Navitor&#x2122; TAVI system, which is already commercially available.
The aortic valve is a heart valve that controls the flow of oxygen-rich blood to the body. With age, calcium may build up in the valve and cause it to narrow – a condition known as aortic stenosis – resulting in the heart needing to work harder to pump blood through the valve. Left untreated, aortic stenosis can cause symptoms, such as chest pain, shortness of breath and fainting, and it can weaken the heart and become life-threatening. Patients who are at risk of open-heart surgery due to age, frailty or having multiple other conditions may benefit from minimally invasive treatment options where a device is delivered to the heart through an artery in the leg. Aortic stenosis remains the most common primary valve disease and its prevalence increases with age, ranging from approximately 2% in adults 70-80 years of age to 9% in adults older than 80 years.1
The investigational system is a type of balloon-expandable TAVI device, which works by crimping the new heart valve on a deflated balloon. The balloon with the mounted valve is then inserted into the body through an artery in the groin and routed up to the heart. Once properly positioned inside the narrowed heart valve, the balloon is inflated to expand the new valve, taking over the function of the patient's narrow native heart valve. The balloon is then deflated and removed from the body.

Comments

Zalatoris Acquisition

Zalatoris Acquisition (TCOAW) Options

No option chain data available. Please try again later

Popular Channels

Tools & Features

Partners & Contributors

About Benzinga