Short interest in Upstream Bio Inc (NASDAQ:UPB) increased during the last reporting period, rising from 230.69K to 647.12K. This put -% of the company's publicly available shares short.

Short interest for Upstream Bio gives investors a sense of the degree to which investors are betting on the decline of Upstream Bio's stock. Short interest data is updated every two weeks.

Based on the recent average volume of 342.97K shares traded per day, it would take 1.89 day(s) for holders of this short interest to close out their positions without sending the stock sharply higher.