Gainers
- Trevena, Inc. TRVN shares rose 15.9 percent to $2.04 in pre-market trading after gaining 2.33 percent on Monday.
- Fennec Pharmaceuticals Inc. FENC rose 12.4 percent to $12.25 in pre-market trading after the company disclosed that it has received Breakthrough Therapy designation by the FDA for PEDMARK.
- ITUS Corporation ITUS rose 9.2 percent to $4.65 in pre-market trading. ITUS and Serametrix disclosed results of a blinded prostate cancer study.
- AnaptysBio, Inc. ANAB shares rose 8.8 percent to $123.83 in pre-market trading on news of positive top-line proof-of-concept data for ANB020 in peanut allergy patients.
- Seven Stars Cloud Group, Inc. SSC shares rose 6.01 percent to $2.47 in pre-market trading after surging 20.73 percent on Monday.
- InspireMD, Inc. NSPR rose 4.8 percent to $2.20 in pre-market trading after the company disclosed that it has received regulatory approval for both CGuard EPS and MGuard Prime in Peru.
- Red Hat, Inc. RHT rose 4.6 percent to $160.05 in pre-market trading after the company reported better-than-expected results for its fourth quarter. The company also issued strong first-quarter and fiscal 2019 earnings and sales guidance.
- Adamas Pharmaceuticals, Inc. ADMS rose 4.4 percent to $25.48 in pre-market trading after gaining 2.43 percent on Monday.
- Semiconductor Manufacturing International Corporation SMI shares rose 4.3 percent to $6.97 in the pre-market trading session after climbing 7.22 percent on Monday.
- GlaxoSmithKline plc GSK shares rose 4.1 percent to $38.98 in pre-market trading after Novartis agreed to sell stake in consumer healthcare joint venture to GSK for $13 billion.
- GGP Inc. GGP shares rose 3.7 percent to $21.97 in pre-market trading. Brookfield Property Partners and GGP's special committee reported a deal for Brookfield to buy all outstanding shares of GGP other than those currently held.
- Vipshop Holdings Limited VIPS rose 3.2 percent to $18.57 in pre-market trading after gaining 5.88 percent on Monday.
- Cheetah Mobile Inc. CMCM rose 2.7 percent to $11.72 in pre-market trading after declining 6.32 percent on Monday.
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Check out these big penny stock gainers and losers
Losers
- Longfin Corp. LFIN fell 19.9 percent to $47.51 after declining 16.62 percent on Monday.
- Overstock.com, Inc. OSTK fell 8.7 percent to $40.70 in pre-market trading after announcing a proposed 4-million-share common stock offering..
- Cerecor Inc. CERC fell 7.2 percent to $4 in pre-market trading after dropping 2.93 percent on Monday.
- InVitae Corp NVTA fell 6.4 percent to $6.55 in pre-market trading after reporting a $50-million common stock offering.
- Geron Corporation GERN shares fell 6.4 percent to $5.60 in pre-market trading after rising 6.03 percent on Monday.
- Gladstone Land Corporation LAND shares fell 5.6 percent to $11.99 in pre-market trading following announcement of common stock offering.
- DryShips Inc. DRYS fell 4.8 percent to $3.81 in the pre-market trading session after gaining 3.36 percent on Monday.
- Daxor Corporation DXR shares fell 4.2 percent to $8.53 in pre-market trading after declining 17.21 percent on Monday.
- Mallinckrodt Public Limited Company MNK fell 3.6 percent to $13.55 in pre-market trading.
- Arcadia Biosciences, Inc. RKDA fell 3.3 percent to $25.38 in pre-market trading after dipping 13.92 percent on Monday.
- Magellan Midstream Partners, L.P. MMP shares fell 3.2 percent to $57 in pre-market trading after rising 1.17 percent on Monday.
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