Kazia Therapeutics Stock Is Trading Higher On Paxalisib Licensing Agreement In Greater China

Kazia Therapeutics Ltd KZIA has entered into a licensing agreement with Simcere Pharmaceutical Group Ltd to develop and commercialize Kazia's investigational new drug, paxalisib, in Greater China.

  • Kazia retains rights to the development and commercialization of paxalisib in all other territories and will continue to drive forward the GBM AGILE pivotal study as planned, including in China.
  • Under the terms of the agreement, Kazia will receive an upfront payment of $11 million, including $7 million in cash and a $4 million equity investment.
  • Kazia will also receive milestone payments of up to $281 million for glioblastoma, with further milestones payable for indications beyond glioblastoma, as well as mid-teen percentage royalties on commercial sales.
  • Paxalisib is a brain-penetrant inhibitor of the PI3K / Akt / mTOR pathway, which is disordered in the vast majority of patients with glioblastoma, a common and aggressive form of primary brain cancer.
  • Kazia will hold a conference call to discuss the partnership with Simcere further at 5:00 p.m. E.T. today.
  • Price Action: KZIA shares are trading 26.4% higher at $14.01 in premarket trading on the last check Monday.
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