BeiGene's Zanubrutinib Fails To Meet Efficacy Endpoints In Mid-Stage COVID-19 Study

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  • BeiGene Ltd BGNE has announced data from Phase 2 trial evaluating Brukinsa (zanubrutinib) in hospitalized COVID-19 patients, requiring supplemental oxygen without mechanical ventilation.
  • The study did not meet the co-primary efficacy endpoints of respiratory failure-free survival or reduction in days on oxygen compared to placebo.
  • There were no new or additional safety signals for zanubrutinib identified in the trial.
  • BeiGene expects to submit these data for scientific presentation or publication in the future.
  • Brukinsa is a small molecule inhibitor of Bruton's tyrosine kinase (BTK).
  • Price Action: BGNE shares closed 2.3% lower at $321.60 on Wednesday.
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