- iBio Inc IBIO has provided an update on its IBIO-201 program and reported its progress in developing a second-generation subunit vaccine candidate, IBIO-202, being designed for the prevention of SARS-CoV-2 infection.
- IBIO-201 combines antigens derived from the spike protein ("S protein") fused with iBio's patented LicKM booster molecule
- It recently completed IND-enabling toxicology studies. No adverse effects at low or high doses were identified.
- The Company also reported on the development of IBIO-202, a subunit vaccine candidate that targets the nucleocapsid protein ("N protein") of SARS-CoV-2.
- "In light of the successful global roll-out of COVID-19 vaccines targeting the S protein and the emergence of variant strains of the disease, we decided to focus our efforts on the continued development of IBIO-202 as a differentiated vaccine candidate," said Tom Isett, Chairman, and CEO.
- iBio has expressed N protein antigens and initiated intramuscular and intranasal preclinical studies to identify favorable antigen-adjuvant combinations using its plant-based FastPharming System.
- Results are expected in early Q1 FY2022.
- Price Action: IBIO shares are 30.4% at $1.80 during premarket trading on the last check Friday.
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