Before 10 a.m. ET Wednesday, 138 stocks hit new 52-week highs.

Areas of Significance:

• Microsoft MSFT was the company with the largest market cap to set a new 52-week high.
• The smallest company when considering market cap to set a new 52-week high was Eastside Distilling EAST.
• Data Storage DTST's stock moved significantly upwards, trading 61.04% up to reach a new 52-week high.

Here is a list of stocks that set new 52-week highs during the first half-hour of trading on Wednesday:

• Microsoft MSFT shares were up 0.41% for the day, having made a 52-week high of $279.95.
• Amazon.com AMZN shares broke to $3,734.20 on Wednesday, setting a new 52-week high with a change of up 1.1%.
• Alphabet GOOG stock set a new 52-week high of $2,612.80 Wednesday morning. Over the session, the stock traded up 0.07%.
• Alphabet GOOGL shares were up 0.15% for the day, having made a 52-week high of $2,545.68.
• Visa V shares were up 0.37% for the day, having made a 52-week high of $241.04.
• NVIDIA NVDA shares reached a new 52-week high of $834.95 on Wednesday morning, moving down 0.84%.
• Adobe ADBE shares were up 0.29% for the day, having made a 52-week high of $601.88.
• Nike NKE shares achieved a new 52-week high on Wednesday morning, hitting $160.86 with a daily change of up 0.25%.
• Danaher DHR shares broke to $280.50 on Wednesday, setting a new 52-week high with a change of down 0.31%.
• Novo Nordisk NVO shares achieved a new 52-week high on Wednesday morning, hitting $86.01 with a daily change of up 0.78%.
• Shopify SHOP shares set a new yearly high of $1,586.99 this morning. The stock was up 1.94% on the session.
• Costco Wholesale COST shares were up 0.7% on Wednesday to hit a new 52-week high of $402.20 for a change of up 0.7%.
• American Express AXP shares set a new 52-week high of $172.94 on Wednesday, moving up 1.68%.
• Intuit INTU shares reached a new 52-week high of $506.46 on Wednesday morning, moving up 0.53%.
• BlackRock BLK stock hit a yearly high price of $897.98. The stock was up 0.37% for the day.
• American Tower AMT stock hit a yearly high price of $276.13. The stock was down 0.32% for the day.
• Target TGT stock set a new 52-week high of $247.84 Wednesday morning. Over the session, the stock traded up 0.5%.
• Estee Lauder Cos EL stock made a new 52-week high of $321.90 Wednesday. The stock was up 0.89% for the day.
• Intuitive Surgical ISRG shares broke to a new 52-week high of $959.46 on Wednesday. Shares of the company traded up 0.95%.
• S&P Global SPGI stock set a new 52-week high of $418.21 Wednesday morning. Over the session, the stock traded down 0.15%.
• Zoetis ZTS stock set a new 52-week high of $194.37 Wednesday morning. Over the session, the stock traded down 0.1%.
• Moody's MCO shares hit a new 52-week high of $373.42. The stock traded up 0.45% on the session.
• Edwards Lifesciences EW shares were up 0.61% on Wednesday morning to hit a new 52-week high of $107.25.
• CrowdStrike Holdings CRWD shares were up 0.61% on Wednesday morning to hit a new 52-week high of $269.68.
• IDEXX Laboratories IDXX shares were up 0.51% on Wednesday to hit a new 52-week high of $663.87 for a change of up 0.51%.
• RELX RELX shares hit a yearly high of $27.86. The stock traded up 0.4% on the session.
• Roper Technologies ROP shares hit a yearly high of $480.46. The stock traded up 0.55% on the session.
• Thomson Reuters TRI shares set a new 52-week high of $100.64 on Wednesday, moving up 0.97%.
• IQVIA Holdings IQV shares reached a new 52-week high of $253.35 on Wednesday morning, moving up 0.37%.
• T. Rowe Price Gr TROW stock hit a yearly high price of $204.86. The stock was up 0.13% for the day.
• MSCI MSCI shares set a new 52-week high of $555.64 on Wednesday, moving up 0.43%.
• IHS Markit INFO shares set a new 52-week high of $114.68 on Wednesday, moving up 0.04%.
• Agilent Technologies A shares achieved a new 52-week high on Wednesday morning, hitting $149.48 with a daily change of up 0.15%.
• Fortinet FTNT shares hit a yearly high of $253.20. The stock traded down 0.68% on the session.
• Cintas CTAS stock hit a yearly high price of $386.01. The stock was up 0.65% for the day.
• Motorola Solutions MSI stock made a new 52-week high of $223.84 Wednesday. The stock was down 0.14% for the day.
• ResMed RMD stock hit a yearly high price of $251.18. The stock was up 0.95% for the day.
• Hershey HSY shares broke to $176.00 on Wednesday, setting a new 52-week high with a change of up 0.37%.
• Otis Worldwide OTIS stock hit a yearly high price of $84.08. The stock was up 1.7% for the day.
• SBA Communications SBAC stock set a new 52-week high of $328.46 Wednesday morning. Over the session, the stock traded down 0.21%.
• Cloudflare NET stock set a new 52-week high of $110.94 Wednesday morning. Over the session, the stock traded up 0.52%.
• Liberty Broadband LBRDK shares were up 0.6% for the day, having made a 52-week high of $177.34.
• Copart CPRT shares hit $138.47 on Wednesday morning, setting a new 52-week high for a change of up 0.81%.
• Liberty Broadband LBRDA stock set a new 52-week high of $171.26 Wednesday morning. Over the session, the stock traded up 0.55%.
• Zscaler ZS shares achieved a new 52-week high on Wednesday morning, hitting $231.59 with a daily change of up 0.51%.
• Equifax EFX shares were down 0.02% on Wednesday to hit a new 52-week high of $248.08 for a change of down 0.02%.
• Zebra Technologies ZBRA shares hit $547.79 on Wednesday morning, setting a new 52-week high for a change of up 0.04%.
• HubSpot HUBS shares were up 1.45% on Wednesday to hit a new 52-week high of $616.45 for a change of up 1.45%.
• Arista Networks ANET shares broke to $376.23 on Wednesday, setting a new 52-week high with a change of down 0.93%.
• Garmin GRMN shares broke to a new 52-week high of $147.47 on Wednesday. Shares of the company traded up 0.48%.
• Generac Hldgs GNRC shares broke to a new 52-week high of $438.53 on Wednesday. Shares of the company traded up 1.89%.
• West Pharmaceutical Servs WST shares set a new 52-week high of $372.53 on Wednesday, moving up 0.46%.
• Waters WAT shares achieved a new 52-week high on Wednesday morning, hitting $363.08 with a daily change of up 0.52%.
• Gartner IT stock made a new 52-week high of $255.75 Wednesday. The stock was up 0.45% for the day.
• TransUnion TRU shares broke to a new 52-week high of $113.15 on Wednesday. Shares of the company traded up 0.2%.
• Avantor AVTR stock on Wednesday broke to a yearly high of $36.41. Shares traded down 0.28%.
• Mid-America Apartment MAA shares broke to $174.40 on Wednesday, setting a new 52-week high with a change of down 0.48%.
• Darden Restaurants DRI shares were up 0.68% on Wednesday morning to hit a new 52-week high of $150.20.
• Charles River CRL shares were up 0.38% for the day, having made a 52-week high of $379.72.
• Dynatrace DT shares were up 1.43% on Wednesday morning to hit a new 52-week high of $62.68.
• Carlyle Group CG shares were up 0.19% on Wednesday to hit a new 52-week high of $47.76 for a change of up 0.19%.
• Newegg Commerce NEGG shares were up 31.44% on Wednesday to hit a new 52-week high of $40.88 for a change of up 31.44%.
• American Homes 4 Rent AMH stock hit a yearly high price of $40.25. The stock was down 0.02% for the day.
• Dropbox DBX shares were up 1.13% on Wednesday to hit a new 52-week high of $31.31 for a change of up 1.13%.
• Bruker BRKR shares were up 0.51% on Wednesday to hit a new 52-week high of $78.69 for a change of up 0.51%.
• Ares Management ARES stock hit a yearly high price of $65.60. The stock was up 0.3% for the day.
• Vertiv Holdings VRT shares hit a new 52-week high of $27.81. The stock traded up 0.45% on the session.
• Syneos Health SYNH shares hit a yearly high of $91.87. The stock traded up 0.15% on the session.
• Vimeo VMEO shares reached a new 52-week high of $52.04 on Wednesday morning, moving up 1.37%.
• Globus Medical GMED shares were up 0.74% on Wednesday morning to hit a new 52-week high of $81.06.
• Biohaven Pharma Hldgs BHVN shares hit a new 52-week high of $117.31. The stock traded up 7.95% on the session.
• Omnicell OMCL shares were up 0.58% on Wednesday morning to hit a new 52-week high of $152.93.
• J2 Global JCOM shares were up 0.5% for the day, having made a 52-week high of $142.25.
• Workiva WK stock hit a yearly high price of $121.87. The stock was up 0.6% for the day.
• Descartes Systems Gr DSGX shares were up 0.03% on Wednesday morning to hit a new 52-week high of $70.98.
• Kornit Digital KRNT shares hit a yearly high of $128.49. The stock traded down 0.47% on the session.
• Rapid7 RPD shares reached a new 52-week high of $101.72 on Wednesday morning, moving up 0.66%.
• Synaptics SYNA shares hit a new 52-week high of $158.82. The stock traded up 0.1% on the session.
• Sprout Social SPT stock hit a yearly high price of $95.61. The stock was up 0.45% for the day.
• Vicor VICR shares hit a yearly high of $109.00. The stock traded up 0.81% on the session.
• Apollo Medical Hlgs AMEH shares were up 1.21% on Wednesday morning to hit a new 52-week high of $76.83.
• WNS (Hldgs) WNS shares were up 0.91% on Wednesday morning to hit a new 52-week high of $83.53.
• Alkermes ALKS shares were up 0.04% for the day, having made a 52-week high of $25.72.
• National Storage NSA shares were up 0.36% on Wednesday to hit a new 52-week high of $52.22 for a change of up 0.36%.
• Brookfield Infrastructure BIPC shares hit a new 52-week high of $80.57. The stock traded up 0.13% on the session.
• Calix CALX shares broke to $49.99 on Wednesday, setting a new 52-week high with a change of up 4.5%.
• Criteo CRTO shares hit a new 52-week high of $46.61. The stock traded up 1.46% on the session.
• Perficient PRFT shares hit $83.05 on Wednesday morning, setting a new 52-week high for a change of up 0.9%.
• Domo DOMO shares achieved a new 52-week high on Wednesday morning, hitting $84.00 with a daily change of up 1.94%.
• CorVel CRVL shares broke to a new 52-week high of $138.87 on Wednesday. Shares of the company traded up 0.34%.
• Beauty Health SKIN stock made a new 52-week high of $19.50 Wednesday. The stock was up 1.86% for the day.
• Controladora Vuela VLRS stock made a new 52-week high of $21.12 Wednesday. The stock was up 2.96% for the day.
• HeadHunter Group HHR shares broke to $44.60 on Wednesday, setting a new 52-week high with a change of up 3.95%.
• RadNet RDNT shares broke to $36.64 on Wednesday, setting a new 52-week high with a change of up 4.29%.
• Blackrock Municipal 2030 BTT shares set a new yearly high of $26.43 this morning. The stock was up 0.04% on the session.
• iStar STAR shares were up 0.58% on Wednesday to hit a new 52-week high of $20.91 for a change of up 0.58%.
• Tremor Intl TRMR stock hit a yearly high price of $20.19. The stock was down 0.25% for the day.
• Virtus Dividend NFJ shares set a new 52-week high of $15.34 on Wednesday, moving up 0.26%.
• ChipMOS TECHNOLOGIES IMOS shares achieved a new 52-week high on Wednesday morning, hitting $36.47 with a daily change of up 4.75%.
• BellRing Brands BRBR shares were up 1.49% on Wednesday to hit a new 52-week high of $32.97 for a change of up 1.49%.
• Calamos Convertible CHY stock made a new 52-week high of $16.49 Wednesday. The stock was up 0.1% for the day.
• Eaton Vance Enhanced EOS shares set a new yearly high of $23.50 this morning. The stock was up 0.26% on the session.
• BLACKROCK MUNIYIELD MYI shares hit a yearly high of $14.96. The stock traded up 0.22% on the session.
• A10 Networks ATEN shares reached a new 52-week high of $11.94 on Wednesday morning, moving up 2.1%.
• Clarus CLAR stock set a new 52-week high of $27.95 Wednesday morning. Over the session, the stock traded up 1.63%.
• Virtus AllianzGI Equity NIE shares hit a new 52-week high of $30.68. The stock traded up 0.29% on the session.
• Nuveen California NKX stock hit a yearly high price of $16.50. The stock was up 0.43% for the day.
• Ambrx Biopharma AMAM shares set a new yearly high of $20.45 this morning. The stock was up 1.87% on the session.
• Invesco Quality Municipal IQI shares were down 0.22% on Wednesday to hit a new 52-week high of $13.70 for a change of down 0.22%.
• Blackrock Muniyield Fund MYD stock on Wednesday broke to a yearly high of $15.43. Shares traded down 0.07%.
• Blackrock Municipal IT BFK shares achieved a new 52-week high on Wednesday morning, hitting $15.65 with a daily change of up 0.27%.
• BlackRock MuniHoldings MUC shares achieved a new 52-week high on Wednesday morning, hitting $16.15 with a daily change of up 0.25%.
• Blackrock Munivest Fund MVF shares reached a new 52-week high of $9.75 on Wednesday morning, moving up 0.29%.
• Blackstone / GSO BGB shares broke to $14.04 on Wednesday, setting a new 52-week high with a change of up 0.36%.
• Blackrock Muniholdings MFL stock set a new 52-week high of $15.01 Wednesday morning. Over the session, the stock traded up 0.6%.
• Blackrock CA Muni Income BFZ stock on Wednesday broke to a yearly high of $15.09. Shares traded up 0.17%.
• BLACKROCK MUNIHOLDINGS MHN shares were up 0.34% on Wednesday morning to hit a new 52-week high of $14.94.
• PIMCO Income Strategy PFL shares were up 0.06% for the day, having made a 52-week high of $12.97.
• Atento ATTO shares achieved a new 52-week high on Wednesday morning, hitting $29.70 with a daily change of up 1.38%.
• Cohen & Steers Closed-end FOF shares hit a yearly high of $14.69. The stock traded 0.0% (flat) on the session.
• Eaton Vance California EVM shares broke to $12.15 on Wednesday, setting a new 52-week high with a change of down 0.12%.
• Pioneer Muni High Inc MAV stock on Wednesday broke to a yearly high of $12.48. Shares traded up 0.73%.
• Pioneer Floating Rate PHD stock hit a yearly high price of $12.07. The stock was down 0.04% for the day.
• Taiwan Fund TWN shares hit a new 52-week high of $36.67. The stock traded 0.0% (flat) on the session.
• Points International PCOM shares broke to $18.90 on Wednesday, setting a new 52-week high with a change of up 0.62%.
• RiverNorth/DoubleLine OPP shares achieved a new 52-week high on Wednesday morning, hitting $16.04 with a daily change of up 0.06%.
• Codorus Valley Bancorp CVLY stock hit a yearly high price of $20.98. The stock was up 3.57% for the day.
• John Hancock Hedged HEQ shares hit $13.54 on Wednesday morning, setting a new 52-week high for a change of up 0.45%.
• Community West Bancshares CWBC shares achieved a new 52-week high on Wednesday morning, hitting $13.65 with a daily change of up 4.44%.
• MV Oil MVO shares hit a new 52-week high of $9.97. The stock traded up 8.14% on the session.
• Eaton Vance Tax-Managed EXD shares hit a yearly high of $11.84. The stock traded up 0.6% on the session.
• RiverNorth Specialty RSF shares broke to $20.03 on Wednesday, setting a new 52-week high with a change of up 0.42%.
• Invesco High Income Trust VLT shares set a new 52-week high of $15.14 on Wednesday, moving up 0.2%.
• Jakks Pacific JAKK shares hit a new 52-week high of $14.77. The stock traded up 5.02% on the session.
• Opiant Pharmaceuticals OPNT shares hit a yearly high of $18.85. The stock traded up 27.15% on the session.
• Mannatech MTEX shares hit $29.35 on Wednesday morning, setting a new 52-week high for a change of up 0.51%.
• Data Storage DTST stock on Wednesday broke to a yearly high of $13.10. Shares traded up 61.04%.
• Eastside Distilling EAST shares set a new 52-week high of $3.37 on Wednesday, moving up 11.72%.

Stay with Benzinga for further updates about these companies and many others going forward.