Novartis' TGFβ Targeted Antibody Secures FDA Orphan Drug Tag For Pancreatic Cancer

The FDA has granted Orphan Drug Designation to Novartis AG's NVS NIS793 in combination with standard of care chemotherapy to treat pancreatic cancer.
NIS793 is a fully human anti-TGF-β IgG2 monoclonal antibody designed to inhibit the TGF-β pathway in tumor cells and modulate the tumor microenvironment.
A Phase 2 study is ongoing, and a Phase 3 trial in the first-line metastatic pancreatic ductal carcinoma is planned to start enrolling patients later in 2021.
Price Action: NVS shares are up 0.27% at $91.21 during the market session on the last check Tuesday.
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