Illumina, Merck Join Hands For Homologous Recombination Deficiency CDx, Research Assay

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  • Illumina Inc ILMN and Merck & Co Inc MRK provided more details on their partnership to develop and commercialize tests that gauge genetic mutations involved in homologous recombination deficiency (HRD) and identify best responders to PARP inhibitors.
  • Illumina first announced the partnership in January at the JP Morgan Healthcare Conference.
  • Under the terms of the agreement, Illumina will develop a new HRD companion diagnostic for the European Union and UK markets to aid in identifying ovarian cancer patients who are eligible for treatment with olaparib (Lynparza)
  • Lynparza is a PARP inhibitor jointly developed and commercialized by Merck and AstraZeneca Plc AZN.
  • Illumina will also develop a research-use-only HRD assay that will be add-on content for its TSO 500 panel. 
  • The company will launch the RUO assay globally, but not in the US or Japan. 
  • Financial details of the partnership were not disclosed.
  • Price Action: ILMN stock is down 2.38% at $455.88, and MRK stock is down 2.30% at $75.48 during the market session on the last check Tuesday.
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