Novartis Inks $1.3B Protein Degradation Deal With UK's Dunad

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  • The U.K.-based Dunad Therapeutics has entered a strategic collaboration and license agreement with Novartis AG NVS to generate orally bioavailable covalent and protein degrading small molecule drugs.
  • Under the new deal, Dunad is tasked with deploying its platform to generate new candidates against up to four targets and steer those programs up to lead optimization.
  •  Novartis will contribute target and ligand knowledge and assays & models and will fully fund the research collaboration.
  • Novartis has an exclusive option to develop and commercialize products against up to four drug targets. 
  • Under the agreement terms, Dunad will receive $24 million in an upfront payment, equity investment, and research funding.
  • Dunad will also be eligible for milestone payments that could aggregate up to $1.3 billion and royalties.
  • Price Action: NVS shares closed down 0.36% at $83.75 on Tuesday.
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