- Shanghai Junshi Biosciences Co Ltd and Coherus BioSciences Inc CHRS have shared biomarker analyses from the CHOICE-01 Phase 3 trial of toripalimab plus chemotherapy as first-line treatment of advanced squamous or non-squamous non-small cell lung cancer (NSCLC).
- As of October 31, 2021, at the final analysis, a significant improvement in PFS was detected in the toripalimab arm over the placebo arm, with a median PFS of 8.4 vs. 5.6 months.
- The 1-year PFS rates for the toripalimab and placebo arms were 36.7% and 17.2%, respectively.
- Related: Junshi Biosciences, Coherus Share Toripalimab Survival Data In Esophageal Cancer.
- A prespecified interim analysis demonstrated a statistically significant improvement in overall survival for the toripalimab arm over the placebo arm (median OS not reached vs. 17.1 months).
- The addition of toripalimab to standard first-line chemotherapy in patients with advanced NSCLC showed a manageable safety profile with no new safety signals observed.
- Price Action: CHRS shares are up 5.51% at $12.73 during the market session on the last check Tuesday.
© 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
Comments
Loading...
Posted In:
Benzinga simplifies the market for smarter investing
Trade confidently with insights and alerts from analyst ratings, free reports and breaking news that affects the stocks you care about.
Join Now: Free!
Already a member?Sign in