Nature's Ozempic: A Lesser-Known Dietary Supplement Gains Popularity Amid Weight-Loss Craze - WSJ

The weight-loss craze surrounding Ozempic has sparked renewed interest in berberine, a dietary supplement with roots in ancient traditional medicine. Known as “nature’s Ozempic,” berberine has gained popularity on TikTok, where users claim it can aid in weight loss, The Wall Street Journal reports.

Berberine’s Popularity: Berberine, a bright-yellow compound extracted from various plant species, has been used for thousands of years in traditional medicine. In the U.S., it is available as a pill or powder, but it isn’t regulated by the U.S. Food and Drug Administration.

Research Findings: Small studies and rodent research suggest that berberine can decrease blood glucose and cholesterol, and improve insulin resistance. However, researchers warn that studies linking the supplement to weight loss are limited, and other lifestyle changes might contribute to observed shifts.

User Experiences: Some users, like Kiki Mahoney of Knebworth, England, report decreased appetite since taking berberine. However, experts caution that the placebo effect might be at play, and the quality of berberine supplements can vary widely among brands.

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