Gainers
- Tivic Health Systems, Inc. TIVC shares jumped 105% to $0.2050 after the company signed a distribution agreement with Cardinal Health.
- Black Diamond Therapeutics, Inc. BDTX surged 76.3% to $3.2450 after the company announced initial dose escalation data demonstrated anti-tumor activity of BDTX-1535 in non-small cell lung cancer patients across multiple EGFR mutation families.
- Centogene N.V. CNTG rose 49% to $1.1675 after the company and Lifera formed a Saudi Arabian joint venture. Under the terms of the collaboration, the company will receive a $30 million mandatory convertible loan from Lifera.
- CalciMedica, Inc. CALC climbed 37% to $4.43.
- Cara Therapeutics, Inc. CARA gained 22.1% to $3.9547. Cara Therapeutics was granted U.S. Patent #11684674: Oral formulations of kappa opioid receptor agonists.
- AC Immune SA ACIU rose 19.2% to $2.36 after the company received FDA fast track designation for anti-amyloid-beta active immunotherapy, ACI-24.060 for Alzheimer's disease.
- American Equity Investment Life Holding Company AEL shares gained 17.6% to $53.02 after the company announced it has received a $55 per share acquisition proposal from Brookfield Reinsurance.
- American Rebel Holdings, Inc. AREB jumped 16.6% to $5.47.
- Biodexa Pharmaceuticals Plc BDRX rose 16.6% to $0.0729.
- IronNet, Inc. IRNT gained 14.8% to $0.2067 after dropping 13% on Monday.
- Astrotech Corporation ASTC gained 13.5% to $12.95. Astrotech 13D filing showed BML Investment Partners, L.P. increased stake in the company to 13%.
- Aterian, Inc. ATER rose 13% to $0.4099.
- Enovix Corporation ENVX gained 12.1% to $14.71 after the company announced it received a purchase order to produce battery cells for the U.S. Army.
- WeWork Inc. WE rose 11.1% to $0.2601.
- Moolec Science SA MLEC gained 10.7% to $4.1817.
- Edgewise Therapeutics, Inc. EWTX rose 9.9% to $7.54 as the company released 12-month topline results from the ARCH study, an open-label, single-center study assessing EDG-5506 in adults with Becker Muscular Dystrophy (BMD).
- NextPlay Technologies, Inc. NXTP surged 9.7% to $1.13.
- Ispire Technology Inc. ISPR rose 9.6% to $8.52 after the company announced it raised roughly $8 million in a private placement of common stock.
- Unity Software Inc. U gained 9.2% to $40.10 after the company announced a new AI marketplace and Wells Fargo initiated coverage on the stock with an Overweight rating and $48 price target.
- InnSuites Hospitality Trust IHT shares rose 8.8% to $2.84 after gaining 13% on Monday.
- BIOLASE, Inc. BIOL shares gained 8.3% to $0.0852. Biolase was recently notified by Nasdaq that the company did not meet the minimum closing bid price requirement of $1.00 for continued listing.
- View, Inc. VIEW shares climbed 8.2% to $0.13 after declining around 10% on Monday. View recently filed a new patent application titled "Environmental Adjustment Using Artificial Intelligence."
- OneConnect Financial Technology Co., Ltd. OCFT shares gained 7.4% to $2.9650 after dropping 33% on Monday. The company recently reported first-quarter sales of $135.33 million, missing the consensus estimate of $143.91 million.
Losers
- Adicet Bio, Inc. ACET dropped 53.2% to $2.18 after the company shared safety and efficacy data from its Phase 1 study of ADI-001 for relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma (NHL). JMP Securities downgraded Adicet Bio to Market Perform from Market Outperform rating.
- Siyata Mobile Inc. SYTA dipped 40% to $0.0533 after the company priced a 50 million share offering at $0.045 per share.
- Lordstown Motors Corp. RIDE shares fell 31.3% to $1.90 after the company opted to file for Chapter 11 bankruptcy protection.
- Xponential Fitness, Inc. XPOF fell 30.2% to $17.52. Fuzzy Panda Research issued a short report titled 'Xponential Fitness (XPOF) – "Abusive Franchisor That Is A House Of Cards."'
- Nkarta, Inc. NKTX dropped 26.6% to $3.3250 after the company released updated data from its Phase 1 study of NKX101 for relapsed or refractory acute myeloid leukemia.
- Yellow Corporation YELL declined 24.6% to $0.9573. Yellow filed $137M+ lawsuit against the International Brotherhood of Teamsters, alleging breach of contract in blocking efforts to modernize century-old company.
- Bruush Oral Care Inc. BRSH fell 22.9% to $0.2575 after gaining around 10% on Monday.
- Digital Media Solutions, Inc. DMS fell 21.1% to $0.3215 after jumping around 22% on Monday.
- Terns Pharmaceuticals, Inc. TERN dropped 17.4% to $7.94. Terns Pharmaceuticals highlighted new preclinical data for TERN-601 program in obesity at the ADA's 83rd Annual Scientific Session and upcoming events.
- Benitec Biopharma Inc. BNTC fell 16.3% to $0.3012.
- GSR II Meteora Acquisition Corp. GSRM fell 15.8% to $4.1099.
- Viking Therapeutics, Inc. VKTX fell 15.7% to $15.29. Truist Securities reiterated Viking Therapeutics with a Buy and maintained a $32 price target.
- NovaBay Pharmaceuticals, Inc. NBY dipped 15% to $0.7438.
- ReShape Lifesciences Inc. RSLS fell 14.1% to $1.52. ReShape Lifesciences submitted FDA PMA supplement application for the next-generation Lap-Band 2.0.
- iMedia Brands, Inc. IMBI shares dropped 13.6% to $0.1641 after jumping 35% on Monday. iMedia Brands recently announced receipt of second Nasdaq non-compliance notice.
- Akumin Inc. AKU fell 12.2% to $0.2190.
- Madrigal Pharmaceuticals, Inc. MDGL dropped 11.9% to $207.31. Madrigal Pharmaceuticals recently presented Phase 3 MAESTRO-NASH data at the European Association for the Study of the Liver Congress.
- Spark Networks SE LOV fell 9.5% to $0.3801 after jumping 50% on Monday. Spark Networks recently received notice from Nasdaq advising it has determined to deny the company's request for continued listing.
- TMC the metals company Inc. TMC declined 9.4% to $1.25.
- Applied Digital Corporation APLD shares dropped 9.3% to $8.34. Applied Digital sees Q4 revenue of $22 million and net loss of $6.8 million.
- Walgreens Boots Alliance, Inc. WBA dipped 9.2% to $28.70 after the company lowered its FY23 guidance.
- Evelo Biosciences, Inc. EVLO shares fell 9% to $0.1820 after gaining around 18% on Monday. Evelo Biosciences recently won U.S. Patent for prebiotic compositions and methods of use thereof for modulation of the microbiome.
- Acelyrin, Inc. SLRN dropped 8.3% to $21.92.
- Super Group (SGHC) Limited SGHC fell 7% to $2.82.
- TD SYNNEX Corporation SNX declined 7% to $90.89 after the company reported worse-than-expected second-quarter financial results and issued third-quarter adjusted EPS and revenue guidance below estimates.
- CureVac N.V. CVAC dropped 6% to $10.91. CureVac recently dosed the first patient in its Phase 1 study of its cancer vaccine candidate for surgically resected glioblastoma.
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