ARM Holdings Plc (NASDAQ:

) dipped 5.33% to $17.77 in the pre-market session. ARMH's shares have gained 176.03% over the past 52 weeks, while the S&P500 index has just gained 6.91% in the same period. NuVasive Inc (NASDAQ:

) lost 4.94% to $30.00 in the pre-market session. NUVA has narrowed its 2010 revenue guidance range from $485 million - $500 million to $485 - $495 million. Arena Pharmaceuticals Inc (NASDAQ:

) fell 3.94% to $6.58 in the pre-market session. Analysts at Barclays downgrade ARNA from "equal weight" to "underperform." THQ Inc (NASDAQ:

) slipped 3.75% to $3.59 in the pre-market trading. THQI had announced the release of “Truth or Lies” in the North America. Read more