Analysts at Jefferies downgraded Ampio Pharmaceuticals AMPE from Buy to Hold.
The target price for Ampio Pharmaceuticals has been lowered from $14 to $5.
Ampio Pharmaceuticals shares have fallen 15.02% over the past 52 weeks, while the S&P 500 index has surged 19.77% in the same period.
Ampio Pharmaceuticals' shares rose 0.71% to $5.70 in pre-market trading.
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