Benzinga's Top #PreMarket Losers

Myriad Genetics Inc. MYGN shares declined 16.92% to $31.67 in pre-market trading after the company cut its full-year outlook and announced the retirement of its CEO Peter Meldrum. Gilead Sciences Inc. GILD shares dropped 5.81% to $100.95 in pre-market trading after the company beat fourth-quarter estimates, but offered a forecast below expectations. Rex Energy Corporation REXX shares fell 4.40% to $4.78 in pre-market trading after gaining 23.46% on Tuesday. Wynn Resorts Ltd. WYNN fell 4.33% to $149.05 in pre-market trading after the company reported financial results for the fourth quarter and missed analyst expectations. Isis Pharmaceuticals, Inc.ISIS shares dropped 3.99% to $62.121 in pre-market trading after falling 5.78% on Tuesday.